List of Targeted Therapy Drugs Approved for Specific Types of Cancer
The FDA has approved targeted therapy drugs for the treatment of some people with the following types of cancer. Some targeted therapy drugs are listed more than once because they have been approved to treat more than one type of cancer. The generic drug name is listed first, with a brand name in parentheses.
Targeted therapy approved for bladder cancer
Targeted therapy approved for brain cancer
Targeted therapy approved for breast cancer
- abemaciclib (Verzenio)
- ado-trastuzumab emtansine (Kadcyla)
- alpelisib (Piqray)
- anastrozole (Arimidex)
- capivasertib (Truqap)
- elacestrant dihydrochloride (Orserdu)
- everolimus (Afinitor)
- exemestane (Aromasin)
- fam-trastuzumab deruxtecan-nxki (Enhertu)
- fulvestrant (Faslodex)
- goserelin acetate (Zoladex)
- lapatinib ditosylate (Tykerb)
- letrozole (Femara)
- margetuximab-cmkb (Margenza)
- neratinib maleate (Nerlynx)
- olaparib (Lynparza)
- palbociclib (Ibrance)
- pembrolizumab (Keytruda)
- pertuzumab (Perjeta)
- pertuzumab, trastuzumab, and hyaluronidase-zzxf (Phesgo)
- ribociclib (Kisqali)
- ribociclib succinate and letrozole (Kisquali Femara Co-Pack)
- sacituzumab govitecan-hziy (Trodelvy)
- talazoparib tosylate (Talzenna)
- tamoxifen citrate (Soltamox)
- toremifene (Fareston)
- trastuzumab (Herceptin)
- tucatinib (Tukysa)
Targeted therapy approved for cervical cancer
Targeted therapy approved for colorectal cancer
Targeted therapy approved for dermatofibrosarcoma protuberans
Targeted therapy approved for endocrine and neuroendocrine tumors
Targeted therapy approved for endometrial cancer
Targeted therapy approved for esophageal cancer
Targeted therapy approved for head and neck cancer
Targeted therapy approved for gastrointestinal stromal tumor
Targeted therapy approved for giant cell tumor
Targeted therapy approved for kidney cancer
- avelumab (Bavencio)
- axitinib (Inlyta)
- belzutifan (Welireg)
- bevacizumab (Avastin)
- cabozantinib-s-malate (Cabometyx)
- everolimus (Afinitor)
- ipilimumab (Yervoy)
- lenvatinib mesylate (Lenvima)
- nivolumab (Opdivo)
- pazopanib hydrochloride (Votrient)
- pembrolizumab (Keytruda)
- sorafenib tosylate (Nexavar)
- sunitinib malate (Sutent)
- temsirolimus (Torisel)
- tivozanib hydrochloride (Fotivda)
Targeted therapy approved for leukemia
- acalabrutinib (Calquence)
- alemtuzumab (Campath)
- asciminib hydrochloride (Scemblix)
- avapritinib (Ayvakit)
- blinatumomab (Blincyto)
- bosutinib (Bosulif)
- brexucabtagene autoleucel (Tecartus)
- dasatinib (Sprycel)
- duvelisib (Copiktra)
- enasidenib mesylate (Idhifa)
- gemtuzumab ozogamicin (Mylotarg)
- gilteritinib fumarate (Xospata)
- glasdegib maleate (Daurismo)
- ibrutinib (Imbruvica)
- idelalisib (Zydelig)
- imatinib mesylate (Gleevec)
- inotuzumab ozogamicin (Besponsa)
- ivosidenib (Tibsovo)
- lisocabtagene maraleucel (Breyanzi)
- midostaurin (Rydapt)
- nilotinib (Tasigna)
- obinutuzumab (Gazyva)
- ofatumumab (Arzerra)
- olutasidenib (Rezlidhia)
- pemigatinib (Pemazyre)
- pirtobrutinib (Jaypirca)
- ponatinib hydrochloride (Iclusig)
- quizartinib dihydrochloride (Vanflyta)
- rituximab (Rituxan)
- rituximab and hyaluronidase human (Rituxan Hycela)
- tagraxofusp-erzs (Elzonris)
- tisagenlecleucel (Kymriah)
- tretinoin (Vesanoid)
- venetoclax (Venclexta)
- zanubrutinib (Brukinsa)
Targeted therapy approved for liver and bile duct cancer
- atezolizumab (Tecentriq)
- bevacizumab (Avastin)
- cabozantinib-s-malate (Cabometyx)
- durvalumab (Imfinzi)
- futibatinib (Lytgobi)
- ipilimumab (Yervoy)
- ivosidenib (Tibsovo)
- lenvatinib mesylate (Lenvima)
- nivolumab (Opdivo)
- pembrolizumab (Keytruda)
- pemigatinib (Pemazyre)
- ramucirumab (Cyramza)
- regorafenib (Stivarga)
- sorafenib tosylate (Nexavar)
- tremelimumab-actl (Imjudo)
Targeted therapy approved for lung cancer
- adagrasib (Krazati)
- afatinib dimaleate (Gilotrif)
- alectinib (Alecensa)
- amivantamab-vmjw (Rybrevant)
- atezolizumab (Tecentriq)
- bevacizumab (Avastin)
- binimetinib (Mektovi)
- brigatinib (Alunbrig)
- capmatinib hydrochloride (Tabrecta)
- cemiplimab-rwlc (Libtayo)
- ceritinib (Zykadia)
- crizotinib (Xalkori)
- dabrafenib mesylate (Tafinlar)
- dacomitinib (Vizimpro)
- durvalumab (Imfinzi)
- encorafenib (Braftovi)
- entrectinib (Rozlytrek)
- erlotinib hydrochloride (Tarceva)
- fam-trastuzumab deruxtecan-nxki (Enhertu)
- gefitinib (Iressa)
- ipilimumab (Yervoy)
- lazertinib mesylate hydrate (Lazcluze)
- lorlatinib (Lorbrena)
- necitumumab (Portrazza)
- nivolumab (Opdivo)
- osimertinib mesylate (Tagrisso)
- pembrolizumab (Keytruda)
- pralsetinib (Gavreto)
- ramucirumab (Cyramza)
- repotrectinib (Augtyro)
- selpercatinib (Retevmo)
- sotorasib (Lumakras)
- tarlatamab-dlle (Imdelltra)
- tepotinib hydrochloride (Tepmetko)
- trametinib dimethyl sulfoxide (Mekinist)
- tremelimumab-actl (Imjudo)
Targeted therapy approved for lymphoma
- acalabrutinib (Calquence)
- axicabtagene ciloleucel (Yescarta)
- belinostat (Beleodaq)
- bexarotene (Targretin)
- bortezomib (Velcade)
- brentuximab vedotin (Adcetris)
- brexucabtagene autoleucel (Tecartus)
- crizotinib (Xalkori)
- denileukin diftitox (Lymphir)
- duvelisib (Copiktra)
- epcoritamab-bysp (Epkinly)
- glofitamab-gxbm (Columvi)
- ibritumomab tiuxetan (Zevalin)
- ibrutinib (Imbruvica)
- lisocabtagene maraleucel (Breyanzi)
- loncastuximab tesirine-lpyl (Zynlonta)
- mogamulizumab-kpkc (Poteligeo)
- mosunetuzumab-axgb (Lunsumio)
- nivolumab (Opdivo)
- obinutuzumab (Gazyva)
- pembrolizumab (Keytruda)
- pemigatinib (Pemazyre)
- pirtobrutinib (Jaypirca)
- polatuzumab vedotin-piiq (Polivy)
- pralatrexate (Folotyn)
- rituximab (Rituxan)
- rituximab and hyaluronidase human (Rituxan Hycela)
- romidepsin (Istodax)
- selinexor (Xpovio)
- siltuximab (Sylvant)
- tafasitamab-cxix (Monjuvi)
- tazemetostat hydrobromide (Tazverik)
- tisagenlecleucel (Kymriah)
- venetoclax (Venclexta)
- vorinostat (Zolinza)
- zanubrutinib (Brukinsa)
Targeted therapy approved for malignant mesothelioma
Targeted therapy approved for multiple myeloma
- bortezomib (Velcade)
- carfilzomib (Kyprolis)
- ciltacabtagene autoleucel (Carvykti)
- daratumumab (Darzalex)
- daratumumab and hyaluronidase-fihj (Darzalex Faspro)
- elranatamab-bcmm (Elrexfio)
- elotuzumab (Empliciti)
- idecabtagene vicleucel (Abecma)
- isatuximab-irfc (Sarclisa)
- ixazomib citrate (Ninlaro)
- talquetamab-tgvs (Talvey)
- selinexor (Xpovio)
- teclistamab-cqyv (Tecvayli)
Targeted therapy approved for myelodysplastic and myeloproliferative disorders
Targeted therapy approved for neuroblastoma
Targeted therapy approved for ovarian epithelial, fallopian tube, and primary peritoneal cancers
Targeted therapy approved for pancreatic cancer
Targeted therapy approved for plexiform neurofibroma
Targeted therapy approved for prostate cancer
- abiraterone acetate (Zytiga)
- apalutamide (Erleada)
- bicalutamide (Casodex)
- cabazitaxel (Jevtana)
- darolutamide (Nubeqa)
- degarelix (Firmagon)
- enzalutamide (Xtandi)
- flutamide
- goserelin acetate (Zoladex)
- leuprolide acetate (Lupron Depot, Eligard)
- leuprolide mesylate (Camcevi)
- lutetium Lu 177 vipivotide tetraxetan (Pluvicto)
- nilutamide (Nilandron)
- niraparib tosylate monohydrate and abiraterone acetate (Akeega)
- olaparib (Lynparza)
- talazoparib tosylate (Talzenna)
- radium 223 dichloride (Xofigo)
- relugolix (Orgovyx)
- rucaparib camsylate (Rubraca)
- triptorelin pamoate (Trelstar)
Targeted therapy approved for skin cancer
- alitretinoin (Panretin)
- atezolizumab (Tecentriq)
- avelumab (Bavencio)
- binimetinib (Mektovi)
- cemiplimab-rwlc (Libtayo)
- cobimetinib fumarate (Cotellic)
- dabrafenib mesylate (Tafinlar)
- encorafenib (Braftovi)
- ipilimumab (Yervoy)
- nivolumab (Opdivo)
- nivolumab and relatlimab-rmbw (Opdualag)
- pembrolizumab (Keytruda)
- retifanlimab-dlwr (Zynyz)
- sonidegib (Odomzo)
- tebentafusp-tebn (Kimmtrak)
- trametinib dimethyl sulfoxide (Mekinist)
- vismodegib (Erivedge)
- vemurafenib (Zelboraf)
Targeted therapy approved for soft tissue sarcoma
Targeted therapy approved for solid tumors anywhere in the body
Targeted therapy approved for stomach (gastric) cancer
Targeted therapy approved for systemic mastocytosis
Targeted therapy approved for thyroid cancer