Adagrasib
This page contains brief information about adagrasib and a collection of links to more information about the use of this drug, research results, and ongoing clinical trials.
FDA label information for this drug is available at DailyMed.
Use in Cancer
Adagrasib is approved to treat adults with cancer that has spread and has an abnormal KRAS gene, including:
- non-small cell lung cancer (NSCLC). It is used in patients who have received at least one other systemic therapy
- colorectal cancer. It is used with cetuximab in patients who have received chemotherapy that included a fluoropyrimidine, oxaliplatin, and irinotecan hydrochloride
These uses are approved under FDA’s Accelerated Approval Program. As a condition of approval, a confirmatory trial(s) must show that adagrasib provides a clinical benefit in these patients.
Adagrasib is also being studied in the treatment of other types of cancer.
More About Adagrasib
Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.
MedlinePlus Information on Adagrasib - A lay language summary of important information about this drug that may include the following:
- warnings about this drug,
- what this drug is used for and how it is used,
- what you should tell your doctor before using this drug,
- what you should know about this drug before using it,
- other drugs that may interact with this drug, and
- possible side effects.
Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied.
Research Results and Related Resources
Can Chemo Help KRAS Inhibitors Work Better Against Pancreatic Cancer?
Targeted Therapy to Treat Cancer
Clinical Trials Accepting Patients
Find Clinical Trials for Adagrasib - Check for trials from NCI's list of cancer clinical trials now accepting patients.