Goserelin Acetate
Goserelin acetate is a type of hormone therapy called a luteinizing hormone-releasing hormone (LHRH) agonist. It initially causes the pituitary gland to make more luteinizing hormone (LH) and follicle-stimulating hormone (FSH), leading to a temporary increase in testosterone levels in men and estrogen levels in women. With continued use, goserelin acetate lowers the amount of LH and FSH the pituitary gland releases, leading to a drop in testosterone levels in men and estrogen levels in women. This may stop or slow the growth of cancer cells that need testosterone or estrogen to grow. Hormones usually return to pretreatment levels a few months after stopping treatment.
FDA label information for this drug is available at DailyMed.
Use in Cancer
Goserelin acetate is approved to treat:
- Breast cancer that is advanced. It is used as palliative treatment in premenopausal and perimenopausal women.
- Prostate cancer. It is used with flutamide and radiation therapy in localized prostate cancer. It is also used as palliative treatment in advanced prostate cancer.
Goserelin acetate is also being studied in conditions related to cancer.
More About Goserelin Acetate
Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.
MedlinePlus Information on MedlinePlus Information for Goserelin Acetate - A lay language summary of important information about this drug that may include the following:
- warnings about this drug,
- what this drug is used for and how it is used,
- what you should tell your doctor before using this drug,
- what you should know about this drug before using it,
- other drugs that may interact with this drug, and
- possible side effects.
Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied.
Research Results and Related Resources
Targeted Therapy to Treat Cancer
Hormone Therapy for Breast Cancer
Hormone Therapy for Prostate Cancer
Clinical Trials Accepting Patients
Find Clinical Trials for Goserelin Acetate - Check for trials from NCI's list of cancer clinical trials now accepting patients.