Tebentafusp-tebn
Tebentafusp-tebn works by bringing healthy T cells (immune cells that help kill cancer cells) and melanoma cells close together so the T cells can more effectively kill the melanoma cells. It does this by binding to a protein called CD3 on healthy T cells and a protein called gp100 on melanoma cells. Tebentafusp-tebn is a type of immunotherapy drug called a bispecific T-cell engager (BiTE).
FDA label information for this drug is available at DailyMed.
Use in Cancer
Tebentafusp-tebn is approved to treat:
- uveal melanoma that cannot be removed by surgery or has spread to other parts of the body. It is used in adults who have the HLA-A*02:01 antigen.
Tebentafusp-tebn is also being studied in the treatment of other types of cancer.
More About Tebentafusp-tebn
Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.
MedlinePlus Information on Tebentafusp-tebn - A lay language summary of important information about this drug that may include the following:
- warnings about this drug,
- what this drug is used for and how it is used,
- what you should tell your doctor before using this drug,
- what you should know about this drug before using it,
- other drugs that may interact with this drug, and
- possible side effects.
Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied.
Research Results and Related Resources
Targeted Therapy to Treat Cancer
Immunotherapy Drug Tebentafusp Improves Survival in Advanced Uveal Melanoma
Clinical Trials Accepting Patients
Find Clinical Trials for Tebentafusp-tebn - Check for trials from NCI's list of cancer clinical trials now accepting patients.