Loncastuximab Tesirine-lpyl
This page contains brief information about loncastuximab tesirine-lpyl and a collection of links to more information about the use of this drug, research results, and ongoing clinical trials.
FDA label information for this drug is available at DailyMed.
Use in Cancer
Loncastuximab tesirine-lpyl is approved to treat:
- B-cell non-Hodgkin lymphoma (NHL), including the following types:
- Diffuse large B-cell lymphoma (DLBCL).
- DLBCL in patients who had low-grade lymphoma.
- High-grade B-cell lymphoma.
It is used in adults whose cancer has relapsed (come back) or has not gotten better after at least two types of systemic therapy.
Loncastuximab tesirine-lpyl is approved under FDA’s Accelerated Approval Program. As a condition of approval, confirmatory trial(s) must show that it provides a clinical benefit in these patients.
Loncastuximab tesirine-lpyl is also being studied in the treatment of other types of cancer.
More About Loncastuximab Tesirine-lpyl
Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.
MedlinePlus Information on Loncastuximab Tesirine-lpyl - A lay language summary of important information about this drug that may include the following:
- warnings about this drug,
- what this drug is used for and how it is used,
- what you should tell your doctor before using this drug,
- what you should know about this drug before using it,
- other drugs that may interact with this drug, and
- possible side effects.
Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied.
Research Results and Related Resources
Clinical Trials Accepting Patients
Find Clinical Trials for Loncastuximab Tesirine-lpyl - Check for trials from NCI's list of cancer clinical trials now accepting patients.