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Therapeutically Applicable Research to Generate Effective Treatments (TARGET)

The Therapeutically Applicable Research to Generate Effective Treatments (TARGET) program applies a comprehensive genomic approach to determine molecular changes that drive childhood cancers.

The goal of the program is to use data to guide the development of more effective, less toxic therapies for children. TARGET is organized into a collaborative network of disease-specific project teams.

Pediatric Cancers Studied by TARGET

The TARGET program molecularly characterized several types of childhood cancers.
GDC Data Portal

Access TARGET Data at the GDC

Access TARGET data at the Genomic Data Commons, along with web-based analysis and visualization tools.

  • Origins and Outcomes of the TARGET Childhood Cancer Program

    NCI’s Therapeutically Applicable Research to Generate Effective Treatments (TARGET) program was started to address the need for more effective therapies for children with cancer. A rich genomic data resource has been generated for several pediatric cancer types.

  • An analysis figure from a meta analysis of TARGET samples.

    Publications by the TARGET Program

    An up-to-date list of publications by Therapeutically Applicable Research to Generate Effective Treatments (TARGET) researchers, including disease-specific, comprehensive, global analyses of the genomic data generated by the program.

  • TARGET Molecular Characterization Platforms

    Descriptions and supporting materials for each of the sequencing platforms and other technologies used to generate the TARGET data set.

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