Clinical Trial Results - Cancer Currents Blog
Reports on findings from cancer clinical trials, with commentary from leading researchers on how the trial results will affect patient care.
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Drug Combination Shrinks Duodenal Polyps in People with Familial Adenomatous Polyposis
In a small clinical trial of people with an inherited condition that greatly increases gastrointestinal cancer risk, a two-drug combination shrank precancerous lesions in the duodenum.
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Video Intervention Helps Prepare Patients to Participate in Cancer Clinical Trials
Patients who took part in a tailored, video-based educational program had a better understanding of and fewer concerns about participating in clinical trials than patients who received text-based educational.
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Two Drugs Show Efficacy against Common Form of Leukemia
Reports from early-stage trials of two new oral drugs provide hope for patients with high-risk chronic lymphocytic leukemia.
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Oncolytic Virus Therapy Shows Benefit in Patients with Melanoma
In a large clinical trial, the oncolytic virus therapy T-VEC improved the durable response rate and median survival in patients with advanced melanoma.
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Study Finds Storytelling Helps Overcome Cervical Cancer Screening Disparities
Using a storytelling approach to educate women about cervical cancer screening eliminated disparities in attitudes toward screening and behavior, according to a new study.
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Adjuvant Chemotherapy Modestly Improves Survival in Some Men with Prostate Cancer
Giving some men with prostate cancer chemotherapy after standard treatment with radiation and hormone therapy modestly improves how long they live, according to results from a new NCI-funded clinical trial.
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The Playing Field for Cancer Checkpoint Inhibitors Is Expanding
The list of cancers that may be susceptible to checkpoint inhibitors is quickly expanding, according to findings from clinical trials presented at the ASCO annual meeting.
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Whole Brain Radiation for Some Patients with Brain Metastases Worsens Cognitive Decline
In some patients with cancer that has spread to the brain, whole brain radiation following radiosurgery causes more severe cognitive decline and does not improve survival compared with radiosurgery alone, a new study has found.
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Trial Yields Positive Data on Pembrolizumab for Lung Cancer, Potential Response Biomarker
Findings from an early phase clinical trial may point to a biomarker that identifies patients with advanced non-small cell lung cancer most likely to respond to the immunotherapy drug pembrolizumab (Keytruda®).
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HPV Vaccine Effective Against Infection at Multiple Sites, Provides Partial Protection in Women with Previous Infections
A new study from NCI researchers finds that the HPV vaccine protects young women from infection with high-risk HPV types at the three primary anatomic sites where persistent HPV infections can cause cancer. The multi-site protection also was observed at lower levels in previously HPV-exposed women.
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Immune-Based Treatment Shows Promise against Metastatic Cervical Cancer
In an early phase NCI clinical trial, two patients with metastatic cervical cancer had a complete disappearance of their tumors after receiving treatment with a form of immunotherapy called adoptive cell transfer.
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Treatment Helps Preserve Fertility for Some Women with Breast Cancer
In a large clinical trial, giving a hormone-suppressing drug helped some younger women with breast cancer get pregnant after completing cancer treatment.