Cancer Currents: An NCI Cancer Research Blog
A blog featuring news and research updates from the National Cancer Institute. Learn more about Cancer Currents.
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Hormone Therapy for Prostate Cancer? A Genetic Test Could Help Decide
For some men with prostate cancer, a genetic biomarker test called Decipher may help predict if their cancer will spread elsewhere in the body. The test could help determine whether hormone therapy, which can cause distressing side effects, is needed.
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Commemorating the Contributions of Cancer Research Greats
Following the death of Dr. Emil Freireich in February, NCI Director Norman E. Sharpless reflects on the accomplishments and legacies of Dr. Freireich and several other cancer research luminaries who have passed in recent years.
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Imaging Test Could Help Guide Breast Cancer Treatment Decisions
For some people with ER-positive breast cancer, a new imaging test may help guide decisions about receiving hormone therapy, according to a new study. The test can show whether estrogen receptors in tumors are active and responsive to estrogen.
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For Cancer Screening, COVID-19 Pandemic Creates Obstacles, Opportunities
After a steep drop in screening for common cancers early in the COVID-19 pandemic, researchers are now exploring ways to improve cancer screening during the current crisis and beyond.
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Oncotype DX Breast Cancer Test May Be Less Accurate for Black Patients
The test, which helps guide treatment decisions, was not as good at predicting the risk of death from breast cancer for Black patients as for White patients, a new study has found. The findings highlight the need for greater racial diversity in research studies.
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Rate of Suicides Related to Cancer Is Declining
Cancer-related suicides dipped each year between 1999 and 2018 in the United States, a recent study has found. Yet, people who have had cancer remain at high risk for suicide and improvements in supportive care are needed, experts say.
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Cancer Researchers Bring Tools, Experience to COVID-19 Studies
Since the COVID-19 pandemic began, cancer researchers have brought their expertise to coronavirus studies. Their findings have ranged from insights into how the SARS-CoV-2 virus enters cells to the identification of potential COVID-19 therapies.
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Commemorating and Making History: The National Cancer Act 50th Anniversary
The week after the globe recognized World Cancer Day and NCI staff were honored with a virtual visit from First Lady Dr. Jill Biden, the NCI director kicks off the commemoration of the 50th anniversary of the National Cancer Act of 1971.
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PDX Mouse Models Are Reliable Stand-Ins for Human Tumors, Study Finds
A large study from an international group of researchers provides reassurance that cancer models, known as PDX mice, largely retain the genetics of the human tumors from which they were created. PDX mice are increasingly used in cancer research.
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Study Explores Jaw Problem Linked to Zoledronic Acid, Finds Risk Factors
A recent study quantified the risk of osteonecrosis of the jaw for patients who take zoledronic acid to manage complications from cancer that has spread to the bone. The study also examined risk factors for osteonecrosis of the jaw in these patients.
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Relugolix Approval Expected to Alter Treatment for Advanced Prostate Cancer
FDA’s recent approval of relugolix (Orgovyx) is expected to affect the treatment of men with advanced prostate cancer. A large clinical trial showed that relugolix was more effective at reducing testosterone levels than another common treatment.
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Obesity May Help Tumors Survive and Grow, Mouse Study Suggests
Obesity changed the relationship between cancer cells and nearby immune cells in ways that helped tumors survive and grow, a study in mice showed. But altering tumor cell metabolism helped immune cells once again recognize and infiltrate tumors.
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Study Suggests a Link between Stress and Cancer Coming Back
Cancer cells that are leftover after treatment can go into a “dormant” state for years. A new study in mice suggests that stress hormones may trigger a chain reaction that wakes up dormant cancer cells, causing tumors to form again.
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The Cancer Moonshot: A Midpoint Progress Update
With the Cancer Moonshot having reached its midway point, NCI Director Dr. Ned Sharpless and Deputy Director Dr. Dinah Singer provide a report on the progress to date and future directions for this ambitious initiative to accelerate progress against cancer.
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Trial Tests Abemaciclib As New Option for Early-Stage Breast Cancer
The drug abemaciclib (Verzenio) may be a new treatment option for people with the most common type of breast cancer, with new study findings suggesting that it can reduce the risk of the cancer returning.
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New on NCI’s Websites for December 2020
NCI periodically provides updates on new websites and other online content of interest to the cancer community. See selected content that has been added as of December 2020.
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Steroids May Limit the Effectiveness of Immunotherapy for Brain Cancer
In people with glioblastoma and other brain cancers, steroids appear to limit the effectiveness of immunotherapy drugs, a new study shows. The findings should influence how steroids are used to manage brain tumor symptoms, researchers said.
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Fertility Preservation Safe for Young Women with Breast Cancer
Fertility preservation for young women with breast cancer doesn’t increase their risk of dying in the ensuing decades, a new study affirmed. Experts said the findings support routinely offering fertility preservation to patients who want it.
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SARS-CoV-2 Antibodies Can Protect from Reinfection, NCI Study Suggests
In a study using data from more than 3 million people, NCI researchers have found that people who have antibodies to SARS-CoV-2, the virus that causes COVID-19, appear to have some degree of protection against being reinfected with the virus.
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Stopping TKI Treatment Is Safe, Improves Quality of Life for Some with CML
For adults with CML who are in a sustained deep molecular remission, stopping treatment with a tyrosine kinase inhibitor is safe and improves their quality of life, a study shows. But researchers cautioned that these patients must be closely monitored.