September 2019 - Cancer Currents Blog
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Selpercatinib Shows Promise against Lung Cancers with Alterations in RET GeneThe investigational drug selpercatinib may benefit patients with lung cancer whose tumors have alterations in the RET gene, including fusions with other genes, according to results from a small clinical trial.
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For Children with Neuroblastoma, Trial Results Highlight Continued Evolution of TreatmentFor many children with high-risk neuroblastoma, receiving two separate stem cell transplants is more beneficial than receiving one, according to the results of an NCI-supported clinical trial conducted by the Children’s Oncology Group.
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FDA Approves Entrectinib Based on Tumor Genetics Rather Than Cancer TypeFDA has approved entrectinib (Rozlytrek) for the treatment of children and adults with tumors bearing an NTRK gene fusion. The approval also covers adults with non-small cell lung cancer harboring a ROS1 gene fusion.
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Pediatricians’ Offices Can Help Parents Quit Smoking, Study ShowsResearchers tested a program that trains pediatricians’ offices to provide smoking cessation treatment to parents during visits with their child’s doctor. The approach is intended to reach adults who are motivated to quit to protect their child’s health.
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To Treat Pancreatic Cancer, Mouse Study Suggests Altering Tumor MicrobiomeIn people with pancreatic cancer, the makeup of bacteria that populate their tumors could predict how long they live, results from a new study suggest. Experiments in mice suggested that altering the tumor microbiome could play a role in treatment.
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For Some Women with Breast Cancer, Cost Influences Decisions about SurgeryIn a survey of nearly 600 breast cancer survivors, researchers found that the cost of care factored into the decisions the women made about what type of surgery to get. Many women also reported never discussing costs with their physicians.
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Building on Success, Maximizing Opportunities: NCI’s Annual Plan & Budget ProposalNCI Acting Director Douglas Lowy, M.D., discusses the institute’s Annual Plan & Budget Proposal for Fiscal Year 2021, which includes the institute’s professional judgement on the funding required to make the most rapid progress against cancer.
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Altering Diet Enhances Response to Cancer Treatments in MiceA new NCI-supported study showed that altering cancer cell metabolism by feeding mice a diet very low in the nutrient methionine improved the ability of chemotherapy and radiation therapy to shrink tumors.