Cancer Currents: An NCI Cancer Research Blog
A blog featuring news and research updates from the National Cancer Institute. Learn more about Cancer Currents.
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NCI ALMANAC: A New Tool for Research on Cancer Drug CombinationsNCI has released a new, easy-to-use resource called the NCI ALMANAC to help researchers identify potentially promising combinations of cancer drugs.
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Collection of Patient-Reported Outcomes Feasible in Cancer Clinical TrialsCancer patients, even those who are undergoing difficult treatments, are willing to devote time to completing thorough assessments of the side effects they encounter in clinical trials, a new study finds.
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Nanoparticles Create Effective CAR T Cells in Living MiceResearchers have developed a method to genetically engineer cancer-fighting immune cells in living animals using nanoparticles that carry DNA. The new study shows that the resulting immune cells, known as CAR T cells, eliminated leukemia in mice.
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Patients Who Choose No Intervention for Small Thyroid Cancers Report Lack of SupportPatients who choose not to pursue immediate biopsy or treatment for small, asymptomatic thyroid cancers, or suspected cancers, can experience a lack of support from doctors and loved ones, a new study shows.
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PARP Inhibitors May Be Effective in Brain, Other Cancers with IDH MutationsStudies presented at the 2017 AACR annual meeting suggest that therapies which take advantage of the mutations in the IDH gene may be more effective than drugs that block it.
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Making Greater Progress Against Cancer—Not Just a Hope but a RealityActing NCI Director Dr. Doug Lowy discusses what he calls encouraging news in the most recent Annual Report to the Nation and how NCI is helping to achieve further progress against cancer.
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FDA Approves Pembrolizumab for Hodgkin LymphomaThe FDA approved pembrolizumab for the treatment of some adult and pediatric patients with classical Hodgkin lymphoma.
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Studies Identify Potential Treatment Strategies for Pediatric DIPG Brain TumorsTwo studies have identified proteins that drive growth of diffuse intrinsic pontine glioma (DIPG) tumor cells. Blocking these targets with investigational drugs slowed tumor growth in animal models.
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FDA Approves Niraparib as Maintenance Therapy for Recurrent Ovarian CancerThe FDA approved the PARP inhibitor niraparib for use as a maintenance therapy for some women with advanced ovarian cancer.
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FDA Approves Ribociclib, Expands Palbociclib Approval for Metastatic Breast CancerThe FDA has approved a new targeted therapy, ribociclib, and expanded its earlier approval of another targeted therapy, palbociclib, for some women with metastatic breast cancer.
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Advancing the Potential and Promise of Total-Body PET ImagingA total-body PET scanner under development is an ideal example of how NCI and NIH are supporting the development of new research and cancer care-related technologies.
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Avelumab Becomes First Approved Treatment for Patients with Merkel Cell CarcinomaThe FDA has approved the first drug ever for the rare skin cancer, Merkel cell carcinoma, and updated data show an improved tumor response rate and that patients’ tumors continued to respond for at least a year.
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Blinatumomab Extends Survival for Patients with Advanced ALLPatients with previously treated acute lymphoblastic leukemia who received blinatumomab, which encourages the immune system to kill cancer cells, lived longer and experienced fewer side effects than patients given standard chemotherapy.
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Targeted Cancer Drug May Also Help Protect Fertility, Study SuggestsFindings from a new study in mice suggest that a class of targeted cancer drugs may have another use in some younger women being treated for cancer: preserving their fertility.
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Colorectal Cancer Incidence Rising in Young Adults: An Interview with Drs. Philip Rosenberg and William AndersonDrs. Philip Rosenberg and William Anderson of NCI discuss a recent study on which they were coauthors that reported an increase in colorectal cancer incidence among adults under age 50 in the United States.
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Stem-Cell Based Tool May Help Measure Heart Toxicity of Cancer DrugsResearchers have used adult stem cells to create a tool for ranking how toxic a group of cancer drugs, called tyrosine kinase inhibitors, are to human heart cells. Such a test could potentially identify toxic side effects earlier in the drug development process.
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Researchers Use CRISPR Gene-Editing Tool to Help Turn Immune Cells against TumorsUsing a new tool for editing genomes, known as CRISPR, researchers have genetically engineered immune cells and improved the ability of these cells to kill cancer cells in mice.
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FDA Approves New Use for Lenalidomide in Multiple MyelomaThe FDA has approved lenalidomide for use as a maintenance therapy in patients with multiple myeloma who have undergone an autologous stem cell transplant, to help keep the cancer from coming back.
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Putting the Cancer Patient Front and Center: An Interview with NCI’s Dr. Paul JacobsenNCI’s Dr. Paul Jacobsen discusses NCI’s Healthcare Delivery Research Program and its role in advancing innovative research to improve the delivery of cancer care.
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New on NCI Websites for March 2017NCI periodically provides updates on new websites and other online content of interest to the cancer community.