Cancer Currents: An NCI Cancer Research Blog
A blog featuring news and research updates from the National Cancer Institute. Learn more about Cancer Currents.
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Saying YES: Inspiring a Diverse Generation of Cancer ScientistsDrs. Ned Sharpless and Sanya Springfield highlight NCI’s YES program, which is encouraging young students from underrepresented populations to become interested and engaged in cancer research.
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A More Treatable Kind of Metastatic Cancer?People with oligometastatic cancer have only a few metastatic tumors. Researchers are studying whether treating these individual tumors directly with surgery or stereotactic body radiation therapy (SBTR or SABR) can help patients live longer or improve their quality of life.
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Study Reinforces Treatment Idea for Cancer with Microsatellite InstabilityCancer cells with a genetic feature called microsatellite instability-high (MSI-high) depend on the enzyme WRN to survive. A new NCI study explains why and reinforces the idea of targeting WRN as a treatment approach for MSI-high cancer.
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Melanoma Cells Are More Likely to Spread after a Stopover in Lymph NodesMelanoma cells that pass through the lymphatic system before entering the bloodstream are more resistant to cell death and spread more readily than cells that enter the bloodstream directly. The finding could lead to new treatment approaches.
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Reducing Cancer’s Global Burden: A Conversation with NCI’s Dr. Satish GopalDr. Satish Gopal, director of NCI’s Center for Global Health, discusses opportunities for making progress against cancer worldwide, particulary in low- and middle-income countries, many of which are seeing increasing cancer incidence and deaths.
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ACS’s Updated Cervical Cancer Screening Guidelines ExplainedUpdated cervical cancer screening guidelines from the American Cancer Society recommend HPV testing as the preferred approach. NCI’s Dr. Nicolas Wentzensen explains the changes and how they compare with other cervical cancer screening recommendations.
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Are Cancer Patients Getting the Opioids They Need to Control Pain?Efforts to contain the opioid epidemic may be preventing people with cancer from receiving appropriate prescriptions for opioids to manage their cancer pain, according to a new study of oncologists’ opioid prescribing patterns.
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Pazopanib Shows Promise for Children, Adults with Soft Tissue SarcomasFor children and adults with advanced soft tissue sarcoma, adding pazopanib (Votrient) to chemotherapy and radiation before surgery may be a promising treatment option, early results from a clinical trial suggest.
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New on NCI’s Websites for September 2020See selected content that has been added to NCI’s websites as of September 2020, in this Cancer Currents post.
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Many Older Adults Screened Unnecessarily for Common CancersMany older adults are being screened for cancer who no longer need to be, a new study shows. Based on a nationwide survey, the study found that at least half of older US adults had received at least one unnecessary cancer screening test in the previous few years.
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CAR T-Cell Therapy Approved by FDA for Mantle Cell LymphomaA CAR T-cell therapy called brexucabtagene autoleucel (Tecartus) has been approved by the Food and Drug Administration (FDA) for some patients with mantle cell lymphoma. This is the third CAR T-cell therapy approved by FDA for patients with cancer.
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Regular Aspirin Use May Increase Older People’s Risk of Dying from CancerRegular use of low-dose aspirin may increase an older person’s risk of being diagnosed with advanced cancer and of dying from cancer, results from the ASPREE clinical trial suggest. Learn more about what this 19,000-participant study found.
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Having a Heart Attack May Make Breast Cancer Grow FasterA heart-related event, like a heart attack, may make breast cancer grow faster, a new study suggests. In mice, heart attacks accelerated breast tumor growth and human studies linked cardiac events with breast cancer recurrence, researchers reported.
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Trastuzumab May Improve Survival in Women with Rare Endometrial CancerFor some women with HER2-positive uterine serous carcinoma, a rare type of endometrial cancer, treating them with trastuzumab (Herceptin) and chemotherapy may help them live longer, according to updated results from a small clinical trial.
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Study Offers Insights on Health Problems among AYA Cancer SurvivorsA study found that the risk of developing any of 26 chronic health problems was about 50% higher among cancer survivors who were diagnosed as adolescents and young adults, compared with their peers who did not have cancer.
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Scientists Focus on Fusion Proteins in Childhood CancersFusion proteins drive the development of many cancers in children, yet little is known about their biology. NCI’s Fusion Oncoproteins in Childhood Cancers Consortium brings together experts from varied disciplines to investigate these cancers.
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How Does Ovarian Cancer Form? A New Study Points to MicroRNAA microRNA—a molecule made by cells to turn genes on and off—called miR-181a may help high-grade serous ovarian cancer form, a study has found. The scientists think the microRNA could potentially help doctors detect ovarian cancer earlier.
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How CRISPR Is Changing Cancer Research and TreatmentThe gene-editing tool CRISPR is changing the way scientists study cancer, and may change how cancer is treated. This in-depth blog post describes how this revolutionary technology is being used to better understand cancer and create new treatments.
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Liquid Biopsy Detects Brain Cancer and Early-Stage Kidney CancerResults from two studies show that a liquid biopsy that analyzes DNA in blood accurately detected kidney cancer at early and more advanced stages and identified and classified different types of brain tumors.
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Rediscovered Drugs Hit Leukemia from Two Different AnglesTwo rediscovered drugs, bisantrene and brequinar, slowed the growth of acute myeloid leukemia in studies of mice. The drugs blocked the activity of a protein called FTO, killing cancer stem cells and helping the immune system attack the cancer.