Cuadro 2. Aberraciones cromosómicas frecuentes que se observan en STB no rabdomiosarcomatososa
| Histología | Aberración cromosómica | Genes participantes |
| Sarcoma de la parte blanda alveolar | t(x;17)(p11.2;q25) | ASPL/TFE3 [29-31] |
| Histiocitoma fibroso angiomatoide | t(12;16)(q13;p11), t(2;22)(q33;q12), t(12;22)(q13;q12) | FUS/ATF1, EWSR1/CREB1, [32] EWS/ATF1 |
| Sarcoma de células claras | t(12;22)(q13;q12), t(2;22)(q33;q12) | ATF1/EWS, EWSR1/CREB1 |
| Fibrosarcoma congénito (infantil)/nefroma mesoblástico | t(12;15)(p13,q25) | ETV-NTRK3 |
| Dermatofibrosarcoma protuberante | t(17;22)(q22;q13) | COL1A1/PDGFB |
| Fibromatosis desmoide | Trisomía 8 o 20, pérdida de 5q21 | mutaciones CTNNB1 o APC |
| Tumores desmoplásicos de células redondas | t(11;22)(p13;q12) | EWS/WT1 [33] |
| Hemangioendotelioma epitelioide | t(1;3)(p36;q25) [34] | WWTR1/CAMTA1 |
| Sarcoma epitelioide | Desactivación SMARCB1 | SMARCB1 |
| Condrosarcoma mixoide extraesquelético | t(9;22)(q22;q12), t(9:17)(q22;q11), t(9;15)(q22;q21), t(3;9)(q11;q22) | EWSR1/NR4A3, TAF2N/NR4A3, TCF12/NR4A3, TGF/NR4A3 |
| Hemangiopericitoma | t(12;19)(q13;q13.3) and t(13;22)(q22;q13.3) | |
| Tumor miofibroblástico inflamatorio | t(1;2)(q23;q23), t(2;19)(q23;q13), t(2;17)(q23;q23), t(2;2)(p23;q13), t(2;11)(p23;p15) [35] | TPM3/ALK, TPM4/ALK, CLTC/ALK, RANBP2/ALK, CARS/ALK |
| Sarcoma fibromixoide de grado bajo | t(7;16)(q33;p11), t(11;16)(p11;p11) | FUS/CREB3L2, FUS/CREB3L1 |
| Tumor maligno de la vaina del nervio periférico | 17q11.2, pérdida o reordenamiento 10p, 11q, 17q, 22q | NF1 |
| Liposarcoma mixoide/de células redondas | t(12;16)(q13;p11), t(12;22)(q13;q12) | FUS/DD1T3, EWSR/DD1T3 |
| Tumor rabdoide | Desactivación SMARCB1 | SMARCB1 |
| Sarcoma sinovial | t(x;18)(p11.2;q11.2) | SYT/SSX |
| Tumor tenosinovial de células gigantes | t(1;2)(p13;q35) | CSF1 |
| STB = sarcoma de tejido blando | ||
| aAdapted from Sandberg,[25] Slater et al.,[26] Mertens et al.,[27] and Romeo.[28] |
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