Colorectal Cancer Screening: What to Expect An audio-described version of this video is also available. Colorectal Cancer Screening: What to Expect Everyone over the age of 50 should be screened for colorectal cancer. Learn about the three screening methods that work to reduce the chance of death from colorectal cancer: colonoscopy, sigmoidoscopy, and home stool test. Also hear personal stories from people who have gone through colorectal cancer screening.