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Clinical Trials to Treat Adult Metastatic Brain Tumors

Trials 1-25 of 71

Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients with Cancer That Has Spread to the Brain
Status: Active
Location: 234 locations
Stereotactic Radiosurgery or Hippocampus Avoidance Whole-Brain Radiation Therapy with Memantine in Treating Patients with 5 or more Brain Metastases
Status: Active
Location: 47 locations
A Study of Stereotactic Radiosurgery (SRS) and Standard Treatment in People with EGFR-Mutated Lung Cancer That Has Spread to the Brain, ICON-RT Trial
Status: Active
Location: 8 locations
Stereotactic Radiosurgery for the Treatment of Brain Metastases from Small Cell Lung Cancer
Status: Active
Location: 8 locations
Evaluating Penetrance of Anticancer Drugs in the Brain in Patients with Brain Cancer, ADePPT Trial
Status: Active
Location: 7 locations
REMASTer: REcurrent Brain Metastases After SRS Trial
Status: Active
Location: 7 locations
Cs131 Brachytherapy for the Treatment of Recurrent Brain Metastases
Status: Active
Location: 6 locations
Single Fraction Stereotactic Radiosurgery Compared with Fractionated Stereotactic Radiosurgery for Treatment of Intact Metastatic Brain Disease, FRACTIONATE Trial
Status: Active
Location: 7 locations
Datopotamab-Deruxtecan for the Treatment of Patients with HER2 Negative Breast Cancer with Brain Metastasis
Status: Active
Location: 6 locations
Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer
Status: Active
Location: 6 locations
Study of 225Ac-ABD147 to Establish Optimal Dose in Patients With SCLC and LCNEC of the Lung That Previously Received Platinum-based Chemotherapy
Status: Active
Location: 8 locations
Pre-Operative or Post-Operative Stereotactic Radiosurgery in Treating Patients with Operative Metastatic Brain Tumors
Status: Active
Location: 4 locations
A Study of Zipalertinib in Patients With Advanced Non-Small Cell Lung Cancer With Epidermal Growth Factor Receptor (EGFR) Exon 20 Insertions or Other Uncommon Mutation.
Status: Active
Location: 4 locations
A Study to Assess the Safety and Tolerability of AZD1390 Given With Radiation Therapy in Patients With Brain Cancer
Status: Active
Location: 5 locations
SNV1521 in Participants with Advanced Solid Tumors
Status: Active
Location: 4 locations
Dendritic Cell Vaccines against Her2/Her3 and Pembrolizumab for the Treatment of Brain Metastasis from Triple Negative Breast Cancer or HER2+ Breast Cancer or Hormone Receptor Positive Breast Cancer
Status: Active
Location: 3 locations
Study of Stereotactic Radiosurgery With Olaparib Followed by Durvalumab and Physician's Choice Systemic Therapy in Subjects With Breast Cancer Brain Metastases
Status: Active
Location: 3 locations
Nilotinib in Combination with Dabrafenib and Trametinib or Encorafenib and Binimetinib for the Treatment of BRAF V600 Mutant Metastatic or Unresectable Melanoma
Status: Active
Location: 3 locations
A First-In-Human, Phase 1 Study Evaluating Oral TACC3 PPI Inhibitor, AO-252, in Advanced Solid Tumors With or Without Brain Metastases
Status: Active
Location: 3 locations
Study to Assess Safety, Tolerability and Activity of DSB2455 in Participants With Advanced Malignancies
Status: Active
Location: 3 locations
Pre-operative SRS or Post-operative SRS in Treating Cancer Patients with Brain Metastases
Status: Active
Location: 2 locations
Normal Tissue Sparing Whole Brain Radiation Therapy for the Treatment of Patients with Brain Metastases
Status: Active
Location: 2 locations
Assessment of Neurocognitive Function in Patients with Multiple Brain Metastases Undergoing Stereotactic Radiosurgery or Stereotactic Body Radiation Therapy
Status: Active
Location: 2 locations
Frameless Stereotactic Radiosurgery with or without Margins in Treating Brain Metastases in Cancer Patients
Status: Active
Location: 2 locations
Neratinib Plus Capecitabine for the Treatment of Her2-Negative Metastatic Breast Cancer with Brain Metastases, FACT-5 Trial
Status: Active
Location: 2 locations