prednisone
View Patient InformationA synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. After cell surface receptor attachment and cell entry, prednisone enters the nucleus where it binds to and activates specific nuclear receptors, resulting in an altered gene expression and inhibition of proinflammatory cytokine production. This agent also decreases the number of circulating lymphocytes, induces cell differentiation, and stimulates apoptosis in sensitive tumor cell populations.
| Synonym: | delta 1-cortisone Delta(1)-Cortisone deltacortisone deltadehydrocortisone metacortandracin PRD Prednisonum |
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| Foreign brand name: | Adasone Cortancyl Dacortin DeCortin Decortisyl Decorton Deltacortene Deltison Deltra Econosone Meprosona-F Ofisolona Panafcort Panasol-S Paracort Predeltin Predicor Predicorten Prednicort Prednidib Prednilonga Predniment Prednitone Promifen Servisone |
| Abbreviation: | PRED |
| Chemical structure: | 1, 2-dehydrocortisone 1;2-dehydrocortisone 17,21-dihydroxypregna-1,4-diene-3,11,20-trione |
| IND number: | 3574 |
| NSC code: | 10023 |