Cancer Currents: An NCI Cancer Research Blog
A blog featuring news and research updates from the National Cancer Institute. Learn more about Cancer Currents.
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Symposium Brings Rising Global Cancer Burden into Focus
An NCI Cancer Currents blog post about the NCI Global Cancer Research Symposium, which examined ways of increasing research collaboration, particularly in cancer prevention and screening, to reduce the cancer burden.
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Olaratumab Approved to Treat Advanced Soft Tissue Sarcoma
The Food and Drug Administration (FDA) has granted accelerated approval to olaratumab (Lartruvo®) for the treatment of some patients with soft tissue sarcoma.
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Scientists Identify Potential Marker of Resistance to PARP Inhibitors
Findings from a new study from NCI researchers could help predict whether a tumor will respond to a new class of promising cancer drugs, and identifies a potential way to overcome that resistance.
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‘Unexpected’ Vulnerability Creates Treatment Opportunity in Aggressive Type of Lung Cancer
A new study has identified a potentially critical vulnerability in lung cancers that have mutations in the KRAS gene, and showed that a drug already under study may be able to exploit it.
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DINO RNA Molecule Triggers Anticancer Response in Damaged Cells
Studies in cells and mice found that, in cells with damaged DNA, a noncoding RNA called DINO stabilizes the p53 protein and guides the cells into cell death, preventing tumor development.
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Modified Immunotherapy Approach Shows Promise for Leukemia
Researchers have developed an immunotherapy approach that uses immune cells whose natural cancer killing abilities have been enhanced in the lab. In a small clinical trial, the treatment led to remissions in about half of patients with acute myeloid leukemia.
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Metabolomics Study Reveals another Energy Source for Cancer Cells
Researchers have found that cancer cells can use the compound lactate to fuel biochemical reactions and to generate other compounds they need for growth and survival.
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New on NCI Websites for October 2016
An NCI Cancer Currents blog post that provides updates on new NCI websites and other online content of interest to the cancer community.
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Educating Patients about Genetic Test Results: An Interview with Carol Weil about the COMET Study
The recently launched COMET study will examine whether educating patients with cancer about genetic testing will increase their knowledge and reduce their stress levels after receiving genomic testing results.
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Avelumab Induces Sustained Tumor Responses in Some Patients with Rare Skin Cancer
In a phase II clinical trial, some patients with metastatic Merkel cell carcinoma whose cancer has progressed despite treatment with chemotherapy had durable tumor responses to the immunotherapy drug avelumab.
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Study Confirms Benefits of Early Palliative Care for Advanced Cancer
A randomized clinical trial has found that patients who received palliative care along with standard treatment for advanced cancer reported having a better quality of life and mood than patients who did not receive early palliative care.
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TARGET Initiative Fueling Progress against Childhood Leukemia
Research from TARGET, an NCI-funded program supporting genomic analyses of childhood cancers, has led to the launch of several clinical trials of targeted therapies to treat children with acute lymphoblastic leukemia.
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Studies Highlight Potential of Targeting HIF-2 in Kidney Cancer
Two new studies suggest that a new class of drugs can effectively target a molecular driver of the most common type of kidney cancer.
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Many Cancer Caregivers Report Feeling Unprepared for Caregiving Challenges
Many family members who care for loved ones with cancer do not feel adequately prepared for the caregiving tasks they assume and need help to make informed decisions about end-of-life care, according to a new study.
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Chromosomal Instability Score May Predict Response to Cancer Treatment
A new study suggests that a chromosomal instability score may help guide treatment choices for patients with cancer.
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Forging Collaborations to Spur Global Progress against Cancer
NCI and NIH announce efforts to establish international collaborations that can accelerate progress in reducing the global cancer burden.
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Meeting Patients Where They Are: Liberating Clinical Trials Data Under the Cancer Moonshot
NCI’s new application programming interface (API) that allows anyone to build online tools that help people find NCI-supported clinical trials.
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The Impact and Future of the Childhood Cancer Survivor Study: An Interview with Greg Armstrong, M.D.
Dr. Greg Armstrong of the Childhood Cancer Survivor Study discusses this long-running study and its future.
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Pancreatic Cancer Cells May Obtain Nutrients from Neighboring Cells
Pancreatic cancer cells instruct healthy cells around them to provide nutrients they need to survive and grow, a new study suggests.
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Blue Ribbon Panel Report: The Power of the Cancer Community Coming Together
NCI Acting Director Dr. Douglas R. Lowy, M.D., thanks the cancer community for contributing to the Cancer Moonshot Blue Ribbon Panel report, which was presented to the National Cancer Advisory Board on September 7.