Paclitaxel Albumin-stabilized Nanoparticle Formulation
Paclitaxel albumin-stablilized nanoparticle formulation is a different form of the chemotherapy drug paclitaxel, which blocks cell division by interfering with microtubules (cellular structures that help move chromosomes during mitosis) and stopping mitosis (cell division). This eventually causes cells to die. The nanoparticle formulation allows higher doses to be given without increased side effects.
FDA label information for this drug is available at DailyMed.
Use in Cancer
Paclitaxel albumin-stabilized nanoparticle formulation is approved to be used alone or with other drugs to treat:
- Breast cancer that has relapsed or spread to other parts of the body after treatment with other chemotherapy.
- Non-small cell lung cancer that has spread. It is used with carboplatin as the first treatment in patients whose cancer cannot be treated with surgery or radiation therapy.
- Pancreatic cancer that has spread to other parts of the body. It is used with gemcitabine hydrochloride as the first treatment.
Paclitaxel albumin-stabilized nanoparticle formulation is also being studied in the treatment of other types of cancer.
Paclitaxel albumin-stabilized nanoparticle formulation is a form of paclitaxel contained in nanoparticles (very tiny particles of protein). The drug is also called nanoparticle paclitaxel and protein-bound paclitaxel. This form may work better than other forms of paclitaxel and have fewer side effects. For more information about paclitaxel that may apply to paclitaxel albumin-stabilized nanoparticle formulation, see the Drug Information Summary for Paclitaxel.
More About Paclitaxel Albumin-stabilized Nanoparticle Formulation
Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.
MedlinePlus Information on Paclitaxel Albumin-stabilized Nanoparticle Formulation - A lay language summary of important information about this drug that may include the following:
- warnings about this drug,
- what this drug is used for and how it is used,
- what you should tell your doctor before using this drug,
- what you should know about this drug before using it,
- other drugs that may interact with this drug, and
- possible side effects.
Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied.
Clinical Trials Accepting Patients
Find Clinical Trials for Nab-paclitaxel - Check for trials from NCI's list of cancer clinical trials now accepting patients.