BREAKING NEWS
XMRV Not Likely Associated with Human Disease
An NCI-led team of researchers have deciphered the origins of xenotropic murine leukemia virus-related virus (XMRV), undermining claims for the retrovirus's role in human disease. The study results appear online in Science today. For more information, visit the NCI News page.
NEWS
Study Questions Benefit of Surgery versus Watchful Waiting in Some with Prostate Cancer

Long-awaited results from a U.S. clinical trial indicate that, in men diagnosed with localized prostate cancer, surgery did not improve survival or decrease the risk of dying from prostate cancer. After 12 years of follow-up, there was no difference in overall or prostate cancer-specific survival between men randomly assigned to radical prostatectomy and those assigned to watchful waiting, observation with palliative treatment if the disease begins to progress. Read more > >
Cabozantinib Shrinks Tumors and Bone Metastases in Prostate and Other Cancers
Drug also shows promise in ovarian, liver, and breast tumorsAlso in the Journals: Cabozantinib May Shrink Some Rare Thyroid Tumors
End-of-Life Care for Lung Cancer Patients Differs in U.S. and Ontario
Differences in availability of hospice and attitudes toward end-of-life care contributeResearchers Identify New Way Tumor Cells May Adapt to Stressful Conditions
CPT1C protein plays key role and could be a treatment target
A MESSAGE TO READERS
ASCO Coverage
The American Society of Clinical Oncology's 2011 annual meeting will take place June 3–7 in Chicago. This issue of the NCI Cancer Bulletin includes stories on studies released before the meeting. For more ASCO coverage, see the June 14 issue.
IN DEPTH
HPV and Pap Co-Testing Safely Extend Cervical Cancer Screening Intervals
HPV test could become primary screening tool, study showsDespite Early Skepticism, HPV Vaccines Prove Effective
Several characteristics make the virus amenable to vaccine developmentFeatured Clinical Trial: Metformin to Treat Early-Stage Breast Cancer
Will giving metformin after surgery help prevent breast cancer relapse?Scientific Meetings through the Lens of Twitter
How social media is changing the conference experience
UPDATES
FDA Update
- Sunitinib Approved to Treat Pancreatic Neuroendocrine Tumors
Cancer.gov Update
- Updated Tool More Accurately Estimates Breast Cancer Risk for Asian Americans
- NCI Recovery Act Web Site Highlights Community-Based Cancer Care and Job Creation
Notes
- NCI's Douglas R. Lowy and John T. Schiller Awarded Sabin Medal
- Upcoming Cancer Survivors Workshop to Address Stress Management for Caregivers
- NCI Calls for Applications from Cancer Control Practitioners
- Spring 2011 NCI CAM News Released
Selected articles from past issues of the NCI Cancer Bulletin are available in Spanish.
The NCI Cancer Bulletin is produced by the National Cancer Institute (NCI), which was established in 1937. Through basic, clinical, and population-based biomedical research and training, NCI conducts and supports research that will lead to a future in which we can identify the environmental and genetic causes of cancer, prevent cancer before it starts, identify cancers that do develop at the earliest stage, eliminate cancers through innovative treatment interventions, and biologically control those cancers that we cannot eliminate so they become manageable, chronic diseases.
For more information about cancer, call 1-800-4-CANCER or visit http://www.cancer.gov.
NCI Cancer Bulletin staff can be reached at ncicancerbulletin@mail.nih.gov.

