NEWS
I-SPY2: Breast Cancer Trial Aims to Speed Drugs to the Clinic
On March 17, the Foundation for the National Institutes of Health and its Biomarkers Consortium announced the launch of the I-SPY2 breast cancer clinical trial, a novel, adaptive clinical study designed to move promising new drugs into phase III clinical trials more quickly and cost effectively than traditional phase II studies. Read more > >
Many Older Colorectal Cancer Patients Do Not Receive Adjuvant Chemotherapy
Study suggests older patients can receive treatment without excess adverse effectsDrug Slows Progression of Cutaneous T-Cell Lymphoma
Denileukin diftitox extended survival to more than 2 years in placebo-controlled trialPrognostic Marker for Hodgkin Lymphoma Could Improve Care
Biomarker identifies patients who may benefit from aggressive initial therapyNanoparticle-based Therapy Triggers RNA Interference in Human Tumors
The experimental therapy blocked the production of a protein in melanoma cells
COMMENTARY
Guest Director's Update: Improving Delivery of Quality Cancer Care
by Dr. Ann O’Mara and Andrea Denicoff
During a recent meeting with NCI-funded investigators at Memorial Sloan-Kettering Cancer Center in New York, we saw an older gentleman sitting in the waiting room, his wife by his side, with a small tablet PC on his lap. He was, we learned, completing a questionnaire about any symptoms or side effects he was having from the treatment he was undergoing for metastatic prostate cancer. Read more > >
Guest Commentary by Dr. Andrea Barsevick: Fatigue—Is it Normal or Pathological? And How Can We Best Treat It?
Soon experts will meet to discuss state of the science and how research can move forward more efficiently Read more > >
A Conversation with Dr. Ann Berger on Palliative Care at NIH
The head of the Pain and Palliative Care Service talks about her work at the NIH Clinical Center Read more > >
A MESSAGE TO READERS
A Look at Palliative CareIn this issue you will notice several articles related to the important topic of palliative care. For a list of NCI resources on this topic, look for the box at the end of the Guest Director’s Update.
IN DEPTH
Common Genetic Variants Modestly Improve Breast Cancer Risk Models
Study tested the effects of adding genetic information to classic risk factors
Training Providers and Patients to Talk about End-of-Life Care
Interactive curricula help doctors and patients communicate effectively
Treating the Whole Person in the City of Hope Lung Cancer Study
Integrated care includes cancer treatment, symptom relief, and psychological and spiritual support for patients and their families
Featured Clinical Trial: Vaccine Therapy for Patients with Progressive Stage D0 Prostate Cancer
Is the TARP peptide vaccine safe for patients with biochemically recurring prostate cancer?
Palliative Care Education: Focusing on Care and Not Just Disease
Two programs are teaching medical residents the core competencies of palliative care
UPDATES
Notes
- Free Telephone Workshop Series for Cancer Survivors
- Print Your Own Copies of Selected NCI Patient Education Booklets
Selected articles from past issues of the NCI Cancer Bulletin are available in Spanish.
The NCI Cancer Bulletin is produced by the National Cancer Institute (NCI), which was established in 1937. Through basic, clinical, and population-based biomedical research and training, NCI conducts and supports research that will lead to a future in which we can identify the environmental and genetic causes of cancer, prevent cancer before it starts, identify cancers that do develop at the earliest stage, eliminate cancers through innovative treatment interventions, and biologically control those cancers that we cannot eliminate so they become manageable, chronic diseases.
For more information about cancer, call 1-800-4-CANCER or visit http://www.cancer.gov.
NCI Cancer Bulletin staff can be reached at ncicancerbulletin@mail.nih.gov.
