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silmitasertib
An orally bioavailable small-molecule inhibitor of CK2 with potential antineoplastic activity. Silmitasertib selectively binds to and inhibits the enzyme casein kinase II (CK2), which may lead to an inhibition of cellular proliferation. CK2, a protein kinase often overexpressed in a variety of cancer cell types, appears to be correlated with malignant transformation, tumor growth and survival. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonym: | | CK2 inhibitor CX-4945 | |
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| Code name: | | CX-4945 | |
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