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testolactone
A progesterone derivative with antineoplastic activity. Testolactone inhibits steroid aromatase, thereby preventing the formation of estrogen from adrenal androstenedione and reducing endogenous estrogen levels. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
| Synonyms: | | Fludestrin therapeutic testolactone | |
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| US brand name: | | Teslac | |
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| Abbreviation: | | TL | |
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| Code name: | | SQ-9538 | |
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| Chemical structures: | | 1,2,3,4,4a,4b,7,9,10,10a-decahydro-2-hydroxy-2,4b-dimethyl-7-oxo-1-phenanthrenepropionic acid delta-lactone 13-hydroxy-3-0x0-13,17-secoandrosta-1,4-dien-17-oic acid delta-lactone 17alpha-oxo-D-homo-1,4-androstadiene-3,17-dione 1-dehydrotestololactone delta-1-testololactone D-homo-17a-oxaandrosta-1,4-diene-3,17-dione | |
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