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A bifunctional hexitol derivative with potential antineoplastic activity. Dianhydrogalactitol alkylates and cross-links DNA via an epoxide group during all phases of the cell cycle, resulting in disruption of DNA function and cell cycle arrest. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
|Chemical structures:||1,2,5,6 dianhydrogalactitol |
galactitol, 1,2:5,6-dianhydro- (8CI 9CI)