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A recombinant chimeric, mouse-human monoclonal antibody directed against tumor necrosis factor alpha (TNF-alpha), a protein involved in inflammation, cell survival, and apoptosis. Infliximab may be pro- apoptotic or anti-apoptotic, depending on cell type. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
|US brand name:||Remicade|