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A human monoclonal antibody produced in transgenic mice that attaches to the transmembrane epidermal growth factor (EGF) receptor. Panitumumab may inhibit autocrine EGF stimulation of tumor cells that express the EGF receptor, thereby inhibiting tumor cell proliferation. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
|Synonyms:||clone E7.6.3 |
monoclonal antibody ABX-EGF
|US brand name:||Vectibix|