Basic Trial Information
Trial Description
     Summary
     Further Trial Information
     Eligibility Criteria
Trial Contact Information

Basic Trial Information

Trial Description

Summary

This randomized phase II trial studies how well selumetinib and Akt inhibitor MK2206 work compared to mFOLFOX therapy in treating patients with metastatic pancreatic cancer previously treated with chemotherapy. Selumetinib and Akt inhibitor MK2206 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as oxaliplatin, and fluorouracil, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. It is not yet know whether selumetinib and Akt inhibitor MK2206 are more effective than oxaliplatin and fluorouracil in treating patients with metastatic pancreatic cancer.

Further Study Information

PRIMARY OBJECTIVES:

I. To assess overall survival in patients with metastatic pancreatic cancer treated with the combination of AZD6244 hydrogen sulfate and MK-2206 compared to those treated with mFOLFOX.

II. To assess progression free survival (PFS) in patients with metastatic pancreatic cancer treated with the combination of AZD6244 hydrogen sulfate and MK-2206 compared to those treated with mFOLFOX.

SECONDARY OBJECTIVES:

I. To assess the frequency and severity of toxicity associated with the combination of AZD6244 hydrogen sulfate and MK-2206 compared to those with mFOLFOX in this patient population.

II. To assess objective tumor response in the subset of patients with measurable disease (confirmed and unconfirmed complete and partial response) in patients with metastatic pancreatic cancer treated with the combination of AZD6244 hydrogen sulfate and MK-2206 compared to those treated with mFOLFOX.

III. To bank tissue and blood for future translational medicine studies.

OUTLINE: This is a multicenter study. Patients are stratified according to duration of prior systemic therapy line (=< 4 months vs > 4 months) and presence of liver metastasis (yes vs no). Patients are randomized to 1 of 2 treatment arms.

ARM I: Patients receive oxaliplatin intravenously (IV) over 2 hours on days 1 and 15 and fluorouracil IV over 46-48 hours on days 1-2 and 15-16 (mFOLFOX).

ARM II: Patients receive Akt inhibitor MK2206 orally (PO) on days 1, 8, 15, and 22, and selumetinib PO daily on days 1-28.

In all arms, courses repeat every 28 days in the absence of disease progression or unacceptable toxicity.

Blood and paraffin-embedded tumor tissue samples are collected for banking and future correlative studies.

After completion of study treatment, patients are followed up periodically for 3 years.

Eligibility Criteria

Inclusion Criteria:

• Patients must have histologically or cytologically confirmed diagnosis of pancreatic adenocarcinoma; patients with endocrine or neuroendocrine tumors, lymphoma of the pancreas, or ampullary cancer are not eligible

• Patients must have distant metastatic disease; patients with macroscopic residual disease post-resection as the only site of disease are not eligible; patients must not have clinically significant ascites (defined as requiring paracentesis) or have brain metastases

• Patients must have received one line, and no more than one line, of prior gemcitabine chemotherapy for pancreatic cancer; for patients who received treatment for advanced/metastatic disease, there must be documentation of disease progression while on this treatment; for patients who received chemotherapy for treatment in the adjuvant setting, recurrence to a metastatic site must be documented by imaging studies within 6months of completing chemotherapy

• Patients must have measurable and/or non-measurable disease; x-rays, scans. or physical examinations for assessment of measurable disease must have been completed within 28 days prior to registration; x-rays, scans, or other tests for assessment of non-measurable disease must have been completed within 42 days prior to registration; all disease must be assessed and documented on the Baseline Tumor Assessment Form

• Sites must seek additional patient consent for the future use of specimens

• Zubrod performance status of 0-1

• Leukocytes >= 3,000/mcL

• Absolute neutrophil count (ANC) >= 1,500/mcL

• Platelets >= 100,000/mcL

• Hemoglobin >= 9.0 g/dL

• Patients must have adequate kidney function as evidenced by at least ONE of the following:

• Serum creatinine =< 1.5 mg/dL within 14 days prior to registration

• Calculated creatinine clearance >= 60 mL/min; the serum creatinine value used in the calculation must have been obtained within 14 days prior to registration

• Total bilirubin =< 1.5 times institutional upper limit of normal(IULN)

• Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) both =< 2.5 times IULN

• Patients must have an albumin level >= 3.0 g/dL within 14 days prior to registration

• Patients must have an International Normalized Ratio (INR) =< 1.5 times IULN within 14 days prior to registration

• Patients must have an electrocardiogram (ECG) within 14 days prior to registration; patients must have QTcF (by Fridericia's calculation) =< 450 msec (male) or =< 470 msec (female)

• Patients with baseline neuropathy must be =< grade 1 according to Common Terminology Criteria for Adverse Events (CTCAE) v 4.0

• Patients must not have uncontrolled diarrhea or active infection requiring antibiotics and be fully recovered from any previous serious infections within 7 days prior to registration

• Patients must be able to swallow tablets and capsules

• Patients with diabetes must be well controlled with fasting glucose =< grade 1 according to CTCAE v 4.0 within 14 days prior to registration

• Patients with history of congestive heart failure must have an ejection fraction >= 55%within 14 days prior to registration

• Patients must not have any of the following: uncontrolled hypertension, acute coronary syndrome within 6 months prior to registration, poorly controlled angina, New York Heart Association Class II-IV heart failure, prior or current cardiomyopathy, atrial fibrillation, or severe valvular heart disease

• Patients must not have a current or past history of central serous retinopathy, retinal vein occlusion, retinal detachment, or have uncontrolled glaucoma (irrespective of intraocular pressure [IOP])

• No prior malignancy is allowed except for the following: adequately treated basal cell or squamous cell skin cancer, in situ cervical cancer, adequately treated stage I or II cancer from which the patient is currently in complete remission, or any other cancer from which the patient has been disease-free for five years

• Patients must not be pregnant or nursing due to unknown fetal and infant risks; women/men of reproductive potential must have agreed to use an effective contraceptive method during the study plus at least 16 weeks after last dose; a woman is considered to be of "reproductive potential" if she has had menses at any time in the preceding 12 consecutive months; in addition to routine contraceptive methods, "effective contraception" also includes heterosexual celibacy and surgery intended to prevent pregnancy (or with a side-effect of pregnancy prevention) defined as a hysterectomy, bilateral oophorectomy or bilateral tubal ligation; however, if at any point a previously celibate patient chooses to become heterosexually active during the time period for use of contraceptive measures outlined in the protocol, he/she is responsible for beginning contraceptive measures

• Patients must have completed systemic therapy at least 28 days prior to registration, any surgical procedure must have been performed at least 14 days prior to registration, and radiation therapy must be completed at least 7 days prior to registration; patients must have recovered from any of the effects of prior therapies or procedures

• Patients must not plan to receive concurrent chemotherapy, radiotherapy, laxatives, agents known to prolong QTc interval, or agents known to be potent to Cytochrome P450 CYP3A4/5 (CYP3A4/5) or Cytochrome P450 1A2 (CYP1A2)

• Patients must not have received prior treatment with leucovorin calcium, fluorouracil, irinotecan hydrochloride, and oxaliplatin (FOLFIRINOX), FOLFOX, MEK inhibitors, PI3K inhibitors, or AKT inhibitors

Trial Contact Information

Trial Lead Organizations/Sponsors

National Cancer Institute

Vincent Chung

Principal Investigator

U.S.A.
California
	Anaheim
	Kaiser Permanente Medical Center - Anaheim/Orange County
		Han A Koh	Ph: 626-564-3455
	Antioch
	Kaiser Permanente - Deer Valley
		Tatjana Kolevska	Ph: 626-564-3455
	Baldwin Park
	Kaiser Permanente Medical Center - Baldwin Park
		Han A Koh	Ph: 626-564-3455
	Bellflower
	Kaiser Permanente Medical Center - Bellflower
		Han A Koh	Ph: 626-564-3455
	Berkeley
	Alta Bates Summit Comprehensive Cancer Center
		Ari D Baron	Ph: 650-696-4487
			Email: PazE@sutterhealth.org
	Burlingame
	Peninsula Medical Center
		Ari D Baron	Ph: 650-696-4487
			Email: PazE@sutterhealth.org
	Castro Valley
	East Bay Radiation Oncology Center
		James H. Feusner	Ph: 510-450-7600
	Duarte
	City of Hope Comprehensive Cancer Center
		Vincent Chung	Ph: 800-826-4673
			Email: becomingapatient@coh.org
	Fontana
	Kaiser Permanente Medical Center - Fontana
		Han A Koh	Ph: 626-564-3455
	Fremont
	Kaiser Permanente - Fremont
		Tatjana Kolevska	Ph: 626-564-3455
	Fresno
	Kaiser Permanente Fresno Medical Center
		Tatjana Kolevska	Ph: 626-564-3455
	Greenbrae
	Sutter Health Western Division Cancer Research Group
		Ari D Baron	Ph: 650-696-4487
			Email: PazE@sutterhealth.org
	Harbor City
	Kaiser Permanente Medical Center - Harbor City
		Han A Koh	Ph: 626-564-3455
	Hayward
	Kaiser Permanente Medical Center - Hayward
		Tatjana Kolevska	Ph: 626-564-3455
	Irvine
	Kaiser Permanente - Irvine
		Han A Koh	Ph: 626-564-3455
	Los Angeles
	Kaiser Foundation Hospital - West Los Angeles
		Han A Koh	Ph: 626-564-3455
	Kaiser Permanente Medical Center - Los Angeles
		Han A Koh	Ph: 626-564-3455
	USC/Norris Comprehensive Cancer Center and Hospital
		Syma Iqbal	Ph: 323-865-0451
		Syma Iqbal	Ph: 323-865-0451
	Martinez
	Contra Costa Regional Medical Center
		James H. Feusner	Ph: 510-450-7600
	Marysville
	Fremont-Rideout Cancer Center
		Thomas J Semrad	Ph: 916-734-3089
	Modesto
	Kaiser Permanente-Modesto
		Tatjana Kolevska	Ph: 626-564-3455
	Mountain View
	El Camino Hospital Cancer Center
		James H. Feusner	Ph: 510-450-7600
	Oakland
	Alta Bates Summit Medical Center - Summit Campus
		James H. Feusner	Ph: 510-450-7600
	Bay Area Breast Surgeons, Incorporated
		James H. Feusner	Ph: 510-450-7600
	CCOP - Bay Area Tumor Institute
		James H. Feusner	Ph: 510-450-7600
	Epic Care - Oakland
		James H. Feusner	Ph: 510-450-7600
	Highland General Hospital
		James H. Feusner	Ph: 510-450-7600
	Kaiser Permanente-Oakland
		Tatjana Kolevska	Ph: 626-564-3455
	Larry G Strieff MD Medical Corporation
		James H. Feusner	Ph: 510-450-7600
	Tom K Lee, Incorporated
		James H. Feusner	Ph: 510-450-7600
	Orange
	Chao Family Comprehensive Cancer Center at University of California Irvine Medical Center
		Tara E Seery	Ph: 877-827-8839
			Email: ucstudy@uci.edu
	Panorama City
	Kaiser Permanente Medical Group
		Han A Koh	Ph: 626-564-3455
	Redwood City
	Kaiser Permanente Medical Center - Redwood City
		Tatjana Kolevska	Ph: 626-564-3455
	Richmond
	Kaiser Permanente Medical Center - Richmond
		Tatjana Kolevska	Ph: 626-564-3455
	Riverside
	Kaiser Permanente Medical Center - Riverside
		Han A Koh	Ph: 626-564-3455
	Roseville
	Kaiser Permanente Medical Center - Roseville
		Tatjana Kolevska	Ph: 626-564-3455
	Sacramento
	Kaiser Permanente Medical Center - Sacramento
		Tatjana Kolevska	Ph: 626-564-3455
	South Sacramento Kaiser-Permanente Medical Center
		Tatjana Kolevska	Ph: 626-564-3455
	University of California Davis Cancer Center
		Thomas J Semrad	Ph: 916-734-3089
	San Diego
	Kaiser Permanente Medical Center - Kaiser Foundation Hospital - San Diego
		Han A Koh	Ph: 626-564-3455
	San Francisco
	California Pacific Medical Center - California Campus
		Ari D Baron	Ph: 650-696-4487
			Email: PazE@sutterhealth.org
	Kaiser Permanente Medical Center - San Francisco Geary Campus
		Tatjana Kolevska	Ph: 626-564-3455
	San Jose
	Kaiser Permanente Medical Center - Santa Teresa
		Tatjana Kolevska	Ph: 626-564-3455
	San Marcos
	Kaiser Permanente Health Care
		Han A Koh	Ph: 626-564-3455
	San Pablo
	Doctors Medical Center - San Pablo Campus
		James H. Feusner	Ph: 510-450-7600
	San Rafael
	Kaiser Foundation Hospital - San Rafael
		Tatjana Kolevska	Ph: 626-564-3455
	Santa Clara
	Kaiser Permanente Medical Center - Santa Clara Homestead Campus
		Tatjana Kolevska	Ph: 626-564-3455
	Santa Rosa
	Kaiser Permanente Medical Center - Santa Rosa
		Tatjana Kolevska	Ph: 626-564-3455
	Sutter Pacific Medical Foundation
		Ari D Baron	Ph: 650-696-4487
			Email: PazE@sutterhealth.org
	South San Francisco
	Kaiser Permanente Medical Center - South San Francisco
		Tatjana Kolevska	Ph: 626-564-3455
	Stockton
	Kaiser Permanente Medical Facility - Stockton
		Tatjana Kolevska	Ph: 626-564-3455
	Truckee
	Tahoe Forest Cancer Center
		Thomas J Semrad	Ph: 916-734-3089
	Vacaville
	Kaiser Permanente Medical Center - Vacaville
		Tatjana Kolevska	Ph: 626-564-3455
	Vallejo
	Kaiser Permanente Medical Center - Vallejo
		Tatjana Kolevska	Ph: 626-564-3455
	Sutter Solano Medical Center
		Ari D Baron	Ph: 650-696-4487
			Email: PazE@sutterhealth.org
	Walnut Creek
	Kaiser Permanente Medical Center - Walnut Creek
		Tatjana Kolevska	Ph: 626-564-3455
	Woodland Hills
	Kaiser Permanente Medical Cener - Woodland Hills
		Han A Koh	Ph: 626-564-3455
Colorado
	Denver
	Kaiser Permanente of Colorado
		Alexander Menter	Ph: 303-614-1300
	Fort Collins
	Front Range Cancer Specialists
		Diana C. Medgyesy	Ph: 970-212-7600
	Poudre Valley Hospital
		Miho T Scott	Ph: 970-495-8226
	Lafayette
	Kaiser Permanente - Lafayette
		Alexander Menter	Ph: 303-614-1300
Connecticut
	Hartford
	Saint Francis/Mount Sinai Regional Cancer Center at Saint Francis Hospital and Medical Center
		Philip J. Stella	Ph: 734-712-3456
	Middletown
	Middlesex Hospital Cancer Center
		Susanna Hong	Ph: 860-358-2058
Delaware
	Lewes
	Tunnell Cancer Center at Beebe Medical Center
		Stephen Scott Grubbs	Ph: 302-733-6227
	Newark
	Helen F. Graham Cancer Center at Christiana Hospital
		Stephen Scott Grubbs	Ph: 302-733-6227
Florida
	Jacksonville
	Baptist Cancer Institute - Jacksonville
		Troy Hancil Guthrie	Ph: 904-202-7051
	Orlando
	Florida Hospital Cancer Institute at Florida Hospital Orlando
		Lee M. Zehngebot	Ph: 407-303-5623
Georgia
	Decatur
	Charles B. Eberhart Cancer Center at DeKalb Medical Center
		Jayanthi Srinivasiah	Ph: 404-501-3279
	Gainesville
	Northeast Georgia Medical Center
		Charles H. Nash	Ph: 770-219-8800
			Email: cancerpatient.navigator@nghs.com
	Macon
	Medical Center of Central Georgia
		Frederick M. Schnell	Ph: 478-633-1226
	Savannah
	Nancy N. and J. C. Lewis Cancer and Research Pavilion at St. Joseph's/Candler
		Mark A. Taylor	Ph: 912-350-8568
	Valdosta
	Pearlman Comprehensive Cancer Center at South Georgia Medical Center
		Jeffrey M. Hoy	Ph: 229-259-4628
			Email: maryann.heddon@sgmc.org
Hawaii
	Aiea
	Kapiolani Medical Center at Pali Momi
		Jeffrey L. Berenberg	Ph: 808-586-2979
	Honolulu
	Cancer Research Center of Hawaii
		Jeffrey L. Berenberg	Ph: 808-586-2979
	Kaiser Permanente - Moanalua Medical Center and Clinic
		Tatjana Kolevska	Ph: 626-564-3455
	OnCare Hawaii, Incorporated - Kuakini
		Jeffrey L. Berenberg	Ph: 808-586-2979
		Jeffrey L. Berenberg	Ph: 808-586-2979
	OnCare Hawaii, Incorporated - Lusitana
		Jeffrey L. Berenberg	Ph: 808-586-2979
	Queen's Cancer Institute at Queen's Medical Center
		Jeffrey L. Berenberg	Ph: 808-586-2979
	Kailua
	Castle Medical Center
		Jeffrey L. Berenberg	Ph: 808-586-2979
Idaho
	Boise
	Saint Alphonsus Cancer Care Center at Saint Alphonsus Regional Medical Center
		Philip J. Stella	Ph: 734-712-3456
	Meridian
	Idaho Urologic Institute, PA
		Philip J. Stella	Ph: 734-712-3456
Illinois
	Aurora
	Rush-Copley Cancer Care Center
		Ronnie F Luyun	Ph: 800-446-5532
	Chicago
	Louis A. Weiss Memorial Hospital
		Keith L. Shulman	Ph: 773-564-5044
	University of Chicago Cancer Research Center
		Hedy L. Kindler	Ph: 773-834-7424
	University of Illinois Cancer Center
		Neeta K Venepalli	Ph: 312-355-3046
	Decatur
	Decatur Memorial Hospital Cancer Care Institute
		James L. Wade	Ph: 217-876-4740
			Email: kcheek@dmhhs.org
	Elgin
	Sherman Hospital
		James L. Wade	Ph: 217-876-4740
			Email: kcheek@dmhhs.org
	Harvey
	Ingalls Cancer Care Center at Ingalls Memorial Hospital
		Mark F. Kozloff	Ph: 708-915-4673
			Email: clinicaltrials@ingalls.org
	Joliet
	Joliet Oncology-Hematology Associates, Limited - West
		Kulumani M Sivarajan	Ph: 815-730-3098
			Email: maureenc@jolietoncology.com
	Mt. Vernon
	Good Samaritan Regional Health Center
		Bethany G. Sleckman	Ph: 913-948-5588
	Springfield
	Regional Cancer Center at Memorial Medical Center
		James L. Wade	Ph: 217-876-4740
			Email: kcheek@dmhhs.org
	Urbana
	Carle Cancer Center at Carle Foundation Hospital
		Ronnie F Luyun	Ph: 800-446-5532
Indiana
	Beech Grove
	St. Francis Hospital and Health Centers - Beech Grove Campus
		Howard M. Gross	Ph: 765-983-3000
	Elkhart
	Elkhart Clinic, LLC
		Robin Zon	Ph: 574-234-5123
	Elkhart General Hospital
		Robin Zon	Ph: 574-234-5123
	Michiana Hematology-Oncology, PC - Elkhart
		Robin Zon	Ph: 574-234-5123
	Fort Wayne
	Fort Wayne Medical Oncology and Hematology
		Sreenivasa Rao Nattam	Ph: 260-484-8830
			Email: ledgar@fwmoh.com
	Indianapolis
	Central Indiana Cancer Centers - East
		Romnee S Clark	Ph: 317-274-2552
	Indiana University Melvin and Bren Simon Cancer Center
		Romnee S Clark	Ph: 317-274-2552
	St. Francis Hospital Cancer Care Services
		Howard M. Gross	Ph: 765-983-3000
	Kokomo
	Community Cancer Care at Howard Regional Health System
		Robin Zon	Ph: 574-234-5123
	La Porte
	Center for Cancer Therapy at LaPorte Hospital and Health Services
		Robin Zon	Ph: 574-234-5123
	Michigan City
	Saint Anthony Memorial Health Centers
		Ronnie F Luyun	Ph: 800-446-5532
	Mishawaka
	Michiana Hematology-Oncology, PC - Mishawaka
		Robin Zon	Ph: 574-234-5123
	Saint Joseph's Medical Center
		Robin Zon	Ph: 574-234-5123
	Plymouth
	Michiana Hematology Oncology PC - Plymouth
		Robin Zon	Ph: 574-234-5123
	Richmond
	Reid Hospital & Health Care Services
		Howard M. Gross	Ph: 317-783-8918
	South Bend
	CCOP - Northern Indiana CR Consortium
		Robin Zon	Ph: 574-234-5123
	Memorial Hospital of South Bend
		Robin Zon	Ph: 574-234-5123
	Michiana Hematology-Oncology, PC - South Bend
		Robin Zon	Ph: 574-234-5123
	Westville
	Michiana Hematology Oncology-PC Westville
		Robin Zon	Ph: 574-234-5123
Iowa
	Bettendorf
	Hematology Oncology Associates of the Quad Cities
		Shobha R. Chitneni	Ph: 563-355-7733
			Email: kedaprile@rccqc.com
	Davenport
	Genesis Regional Cancer Center at Genesis Medical Center
		George Kovach	Ph: 800-446-6088
			Email: werners@genesishealth.com
	Sioux City
	Mercy Medical Center - Sioux City
		Donald Bruce Wender	Ph: 712-252-0088
	Siouxland Hematology-Oncology Associates, LLP
		Donald Bruce Wender	Ph: 712-252-0088
	St. Luke's Regional Medical Center
		Donald Bruce Wender	Ph: 712-252-0088
Kansas
	Chanute
	Cancer Center of Kansas, PA - Chanute
		Shaker R. Dakhil	Ph: 316-262-4467
	Dodge City
	Cancer Center of Kansas, PA - Dodge City
		Shaker R. Dakhil	Ph: 316-262-4467
	El Dorado
	Cancer Center of Kansas, PA - El Dorado
		Shaker R. Dakhil	Ph: 316-262-4467
	Fort Scott
	Cancer Center of Kansas - Fort Scott
		Shaker R. Dakhil	Ph: 316-262-4467
	Independence
	Cancer Center of Kansas-Independence
		Shaker R. Dakhil	Ph: 316-262-4467
	Kingman
	Cancer Center of Kansas, PA - Kingman
		Shaker R. Dakhil	Ph: 316-262-4467
	Lawrence
	Lawrence Memorial Hospital
		Shaker R. Dakhil	Ph: 316-262-4467
	Liberal
	Cancer Center of Kansas, PA - Liberal
		Shaker R. Dakhil	Ph: 316-262-4467
	McPherson
	Cancer Center of Kansas, PA - McPherson
		Shaker R. Dakhil	Ph: 316-262-4467
	Newton
	Cancer Center of Kansas, PA - Newton
		Shaker R. Dakhil	Ph: 316-262-4467
	Parsons
	Cancer Center of Kansas, PA - Parsons
		Shaker R. Dakhil	Ph: 316-262-4467
	Pratt
	Cancer Center of Kansas, PA - Pratt
		Shaker R. Dakhil	Ph: 316-262-4467
	Salina
	Cancer Center of Kansas, PA - Salina
		Shaker R. Dakhil	Ph: 316-262-4467
	Wellington
	Cancer Center of Kansas, PA - Wellington
		Shaker R. Dakhil	Ph: 316-262-4467
	Wichita
	Associates in Women's Health, PA - North Hillside
		Shaker R. Dakhil	Ph: 316-262-4467
	Cancer Center of Kansas, PA - Medical Arts Tower
		Shaker R. Dakhil	Ph: 316-262-4467
	Cancer Center of Kansas, PA - Wichita
		Shaker R. Dakhil	Ph: 316-262-4467
	CCOP - Wichita
		Shaker R. Dakhil	Ph: 316-262-4467
	Via Christi Cancer Center at Via Christi Regional Medical Center
		Shaker R. Dakhil	Ph: 316-262-4467
	Winfield
	Cancer Center of Kansas, PA - Winfield
		Shaker R. Dakhil	Ph: 316-262-4467
Louisiana
	Baton Rouge
	Ochsner Health Center - Bluebonnet
		Jyotsna Fuloria	Ph: 888-562-4763
	Mansfield
	DeSoto Regional Hospital
		Tannaz Armaghany	Ph: 318-813-1412
	Monroe
	Louisiana State University Health Sciences Center - Monroe
		Tannaz Armaghany	Ph: 318-813-1412
	New Orleans
	CCOP - Ochsner
		Jyotsna Fuloria	Ph: 888-562-4763
	New Orleans Cancer Institute at Memorial Medical Center
		Jyotsna Fuloria	Ph: 888-562-4763
	Ochsner Cancer Institute at Ochsner Clinic Foundation
		Jyotsna Fuloria	Ph: 888-562-4763
	Shreveport
	Feist-Weiller Cancer Center at Louisiana State University Health Sciences
		Tannaz Armaghany	Ph: 318-813-1412
	Highland Clinic
		Tannaz Armaghany	Ph: 318-813-1412
Maine
	Augusta
	Harold Alfond Center for Cancer Care
		Thomas Henry Openshaw	Ph: 207-973-4274
	Bangor
	CancerCare of Maine at Eastern Maine Medical Center
		Thomas Henry Openshaw	Ph: 207-973-4274
Maryland
	Elkton MD
	Union Hospital of Cecil County
		Stephen Scott Grubbs	Ph: 302-733-6227
Michigan
	Adrian
	Hickman Cancer Center at Bixby Medical Center
		Rex B Mowat	Ph: 517-265-0116
		Rex B Mowat	Ph: 517-265-0116
	Ann Arbor
	CCOP - Michigan Cancer Research Consortium
		Philip J. Stella	Ph: 734-712-3456
	Saint Joseph Mercy Cancer Center
		Philip J. Stella	Ph: 734-712-3456
	University of Michigan Comprehensive Cancer Center
		Mark Michael Zalupski	Ph: 800-865-1125
	Dearborn
	Oakwood Cancer Center at Oakwood Hospital and Medical Center
		Philip J. Stella	Ph: 734-712-3456
	Detroit
	Van Elslander Cancer Center at St. John Hospital and Medical Center
		Philip J. Stella	Ph: 734-712-3456
	Wayne State University
		Minsig Choi	Ph: 313-576-9363
	Flint
	Hurley Medical Center
		Philip J. Stella	Ph: 734-712-3456
	Grand Blanc
	Genesys Regional Medical Center
		Philip J. Stella	Ph: 734-712-3456
	Jackson
	Gayle M. Jacob Cancer Center at Allegiance Health
		Philip J. Stella	Ph: 734-712-3456
	Kalamazoo
	Borgess Medical Center
		Raymond Sterling Lord	Ph: 269-373-7458
	Bronson Methodist Hospital
		Raymond Sterling Lord	Ph: 269-373-7458
	West Michigan Cancer Center
		Raymond Sterling Lord	Ph: 269-373-7458
	Lansing
	Sparrow Regional Cancer Center
		Philip J. Stella	Ph: 734-712-3456
	Livonia
	St. Mary Mercy Hospital
		Philip J. Stella	Ph: 734-712-3456
	Monroe
	Community Cancer Center of Monroe
		Rex B Mowat	Ph: 517-265-0116
	Mercy Memorial Hospital - Monroe
		Rex B Mowat	Ph: 517-265-0116
	Pontiac
	St. Joseph Mercy Oakland
		Philip J. Stella	Ph: 734-712-3456
	Port Huron
	Mercy Regional Cancer Center at Mercy Hospital
		Philip J. Stella	Ph: 734-712-3456
	Saginaw
	Seton Cancer Institute at Saint Mary's - Saginaw
		Philip J. Stella	Ph: 734-712-3456
	Saint Joseph
	Lakeside Cancer Specialists, PLLC
		Robin Zon	Ph: 574-234-5123
	Southfield
	Providence Hospital - Southfield
		Michael J. Kraut	Ph: 248-849-5337
			Email: jaswinder.grewal@stjohn.org
	St. Joseph
	Lakeland Regional Cancer Care Center - St. Joseph
		Robin Zon	Ph: 574-234-5123
	Warren
	St. John Macomb Hospital
		Philip J. Stella	Ph: 734-712-3456
Minnesota
	Bemidji
	MeritCare Bemidji
		Preston D. Steen	Ph: 701-234-6161
	Burnsville
	Fairview Ridges Hospital
		Patrick J. Flynn	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Coon Rapids
	Mercy and Unity Cancer Center at Mercy Hospital
		Patrick J. Flynn	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Edina
	Fairview Southdale Hospital
		Patrick J. Flynn	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Fridley
	Mercy and Unity Cancer Center at Unity Hospital
		Patrick J. Flynn	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Hutchinson
	Hutchinson Area Health Care
		Patrick J. Flynn	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Maplewood
	HealthEast Cancer Care at St. John's Hospital
		Patrick J. Flynn	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Minnesota Oncology - Maplewood
		Patrick J. Flynn	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Minneapolis
	Hennepin County Medical Center - Minneapolis
		Patrick J. Flynn	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Virginia Piper Cancer Institute at Abbott - Northwestern Hospital
		Patrick J. Flynn	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	New Ulm
	New Ulm Medical Center
		Patrick J. Flynn	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Robbinsdale
	Humphrey Cancer Center at North Memorial Outpatient Center
		Patrick J. Flynn	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Saint Cloud
	CentraCare Clinic - Women and Children
		Donald J Jurgens	Ph: 877-229-4907
			Email: coborncancercenter@centracare.com
	Coborn Cancer Center
		Donald J Jurgens	Ph: 877-229-4907
			Email: coborncancercenter@centracare.com
	Saint Louis Park
	CCOP - Metro-Minnesota
		Patrick J. Flynn	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Park Nicollet Cancer Center
		Patrick J. Flynn	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Saint Paul
	Regions Hospital Cancer Care Center
		Patrick J. Flynn	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	United Hospital
		Patrick J. Flynn	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Shakopee
	St. Francis Cancer Center at St. Francis Medical Center
		Patrick J. Flynn	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Stillwater
	Lakeview Hospital
		Patrick J. Flynn	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Waconia
	Ridgeview Medical Center
		Patrick J. Flynn	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Willmar
	Willmar Cancer Center at Rice Memorial Hospital
		Patrick J. Flynn	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Woodbury
	Minnesota Oncology - Woodbury
		Patrick J. Flynn	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
Mississippi
	Jackson
	University of Mississippi Cancer Clinic
		Louis V Puneky	Ph: 601-815-6700
Missouri
	Cape Girardeau
	Saint Francis Medical Center
		Bethany G. Sleckman	Ph: 913-948-5588
	Southeast Cancer Center
		Alan Philip Lyss	Ph: 800-392-0936
	Jefferson City
	Goldschmidt Cancer Center
		Alan Philip Lyss	Ph: 800-392-0936
	Rolla
	Mercy Clinic Cancer and Hematology - Rolla
		Robert L Carolla	Ph: 417-269-4520
	Phelps County Regional Medical Center
		Robert L Carolla	Ph: 417-269-4520
	Saint Louis
	CCOP - St. Louis-Cape Girardeau
		Bethany G. Sleckman	Ph: 913-948-5588
	David C. Pratt Cancer Center at St. John's Mercy
		Bethany G. Sleckman	Ph: 913-948-5588
	Mercy Clinic St. Louis Cancer and Breast Institute
		Bethany G. Sleckman	Ph: 913-948-5588
	Missouri Baptist Cancer Center
		Alan Philip Lyss	Ph: 800-392-0936
	Springfield
	Cancer Research for the Ozarks
		Robert L Carolla	Ph: 417-269-4520
	Hulston Cancer Center at Cox Medical Center South
		Robert L Carolla	Ph: 417-269-4520
	St. John's Regional Health Center
		Robert L Carolla	Ph: 417-269-4520
Montana
	Billings
	Billings Clinic Cancer Center - 801 N 29th Street
		Benjamin Thomas Marchello	Ph: 800-648-6274
	CCOP - Montana Cancer Consortium
		Benjamin Thomas Marchello	Ph: 800-648-6274
	Hematology-Oncology Centers of the Northern Rockies - Billings
		Benjamin Thomas Marchello	Ph: 800-648-6274
	St. Vincent Healthcare Cancer Care Services
		Benjamin Thomas Marchello	Ph: 800-648-6274
	Bozeman
	Bozeman Deaconess Cancer Center
		Benjamin Thomas Marchello	Ph: 800-648-6274
		Benjamin Thomas Marchello	Ph: 800-648-6274
	Butte
	St. James Healthcare Cancer Care
		Benjamin Thomas Marchello	Ph: 800-648-6274
	Great Falls
	Benefis Sletten Cancer Institute
		Grant William Harrer	Ph: 406-731-8217
	Helena
	St. Peter's Hospital
		Benjamin Thomas Marchello	Ph: 800-648-6274
	Kalispell
	Kalispell Regional Medical Center
		Benjamin Thomas Marchello	Ph: 800-648-6274
	Missoula
	Montana Cancer Center at St. Patrick Hospital and Health Sciences Center
		Benjamin Thomas Marchello	Ph: 800-648-6274
	Montana Cancer Specialists at Montana Cancer Center
		Benjamin Thomas Marchello	Ph: 800-648-6274
Nebraska
	Kearney
	Good Samaritan Cancer Center at Good Samaritan Hospital
		George K. Bascom	Ph: 308-865-7963
Nevada
	Las Vegas
	CCOP - Nevada Cancer Research Foundation
		John Allan Ellerton	Ph: 702-731-8274
	University Medical Center of Southern Nevada
		John Allan Ellerton	Ph: 702-731-8274
New Jersey
	Camden
	Cancer Institute of New Jersey at Cooper University Hospital - Camden
		Stephen Scott Grubbs	Ph: 302-733-6227
	East Orange
	Veterans Affairs Medical Center - East Orange
		Basil S. Kasimis	Ph: 800-475-2336
			Email: patricia.goyer@med.va.gov
	Englewood
	Dizzy Gillespie Cancer Institute at Englewood Hospital and Medical Center
		Minaxi Jhawer	Ph: 201-894-3456
	Newark
	UMDNJ University Hospital
		Robert Wieder	Ph: 732-235-8675
New York
	Brooklyn
	Kings County Hospital Center
		Jason P Gonsky	Ph: 718-245-3131
	SUNY Downstate Medical Center
		Jason P Gonsky	Ph: 718-245-3131
	Glens Falls
	Charles R. Wood Cancer Center at Glens Falls Hospital
		John P Stoutenburg	Ph: 518-926-6700
	Middletown
	Tucker Center for Cancer Care at Orange Regional Medical Center
		Jeffrey M. Stewart	Ph: 845-342-7609
	Mineola
	Winthrop University Hospital
		Alexander A Hindenburg	Ph: 866-946-8476
	Rochester
	James P. Wilmot Cancer Center at University of Rochester Medical Center
		Jonathan W Friedberg	Ph: 585-275-5830
North Carolina
	Goldsboro
	Wayne Memorial Hospital, Incorporated
		James N. Atkins	Ph: 919-580-0000
	Kinston
	Kinston Medical Specialists
		Peter R. Watson	Ph: 252-559-2200
	Pinehurst
	FirstHealth Moore Regional Community Hospital Comprehensive Cancer Center
		Charles S Kuzma	Ph: 910-715-2200
	Statesville
	Iredell Memorial Hospital
		Ruby A. Grimm	Ph: 704-873-5661
North Dakota
	Bismarck
	Medcenter One Hospital Cancer Care Center
		John T Reynolds	Ph: 701-323-5760
			Email: tfischer@mohs.org
	Mid Dakota Clinic, PC
		John T Reynolds	Ph: 701-323-5760
			Email: tfischer@mohs.org
	St. Alexius Medical Center Cancer Center
		John T Reynolds	Ph: 701-323-5760
			Email: tfischer@mohs.org
	Fargo
	Roger Maris Cancer Center at MeritCare Hospital
		Preston D. Steen	Ph: 701-234-6161
		Preston D. Steen	Ph: 701-234-6161
	Sanford Clinic North-Fargo
		Preston D. Steen	Ph: 701-234-6161
Ohio
	Akron
	McDowell Cancer Center at Akron General Medical Center
		Esther H. Rehmus	Ph: 330-344-6348
	Summa Center for Cancer Care at Akron City Hospital
		Jennifer E Payne	Ph: 330-375-6101
	Barberton
	Barberton Citizens Hospital
		Jennifer E Payne	Ph: 330-375-6101
	Bowling Green
	Wood County Oncology Center
		Rex B Mowat	Ph: 517-265-0116
	Chillicothe
	Adena Regional Medical Center
		J. Philip Kuebler	Ph: 614-566-3275
	Cleveland
	MetroHealth Cancer Care Center at MetroHealth Medical Center
		Bruce J. Averbook	Ph: 216-778-8526
			Email: kbauchens@metrohealth.org
	Columbus
	CCOP - Columbus
		J. Philip Kuebler	Ph: 614-566-3275
	Doctors Hospital at Ohio Health
		J. Philip Kuebler	Ph: 614-566-3275
	Grant Medical Center Cancer Care
		J. Philip Kuebler	Ph: 614-566-3275
	Mount Carmel Health - West Hospital
		J. Philip Kuebler	Ph: 614-566-3275
	Riverside Methodist Hospital Cancer Care
		J. Philip Kuebler	Ph: 614-566-3275
	Zangmeister Center
		J. Philip Kuebler	Ph: 614-566-3275
	Dayton
	CCOP - Dayton
		Howard M. Gross	Ph: 317-783-8918
	David L. Rike Cancer Center at Miami Valley Hospital
		Howard M. Gross	Ph: 317-783-8918
	Good Samaritan Hospital
		Howard M. Gross	Ph: 317-783-8918
	Grandview Hospital
		Howard M. Gross	Ph: 317-783-8918
	Samaritan North Cancer Care Center
		Howard M. Gross	Ph: 317-783-8918
	Delaware
	Grady Memorial Hospital
		J. Philip Kuebler	Ph: 614-566-3275
	Elyria
	Hematology Oncology Center
		Rex B Mowat	Ph: 517-265-0116
	Findlay
	Blanchard Valley Regional Cancer Center
		Howard M. Gross	Ph: 317-783-8918
	Franklin
	Atrium Medical Center
		Howard M. Gross	Ph: 317-783-8918
	Greenville
	Wayne Hospital
		Howard M. Gross	Ph: 317-783-8918
	Kettering
	Charles F. Kettering Memorial Hospital
		Howard M. Gross	Ph: 317-783-8918
	Lancaster
	Fairfield Medical Center
		J. Philip Kuebler	Ph: 614-566-3275
	Lima
	Lima Memorial Hospital
		Rex B Mowat	Ph: 517-265-0116
	St. Rita's Medical Center
		Henry Gerad	Ph: 419-226-9617
	Marietta
	Strecker Cancer Center at Marietta Memorial Hospital
		J. Philip Kuebler	Ph: 614-566-3275
	Maumee
	Northwest Ohio Oncology Center
		Rex B Mowat	Ph: 517-265-0116
		Rex B Mowat	Ph: 517-265-0116
	Mount Vernon
	Knox Community Hospital
		J. Philip Kuebler	Ph: 614-566-3275
	Newark
	Licking Memorial Cancer Care Program at Licking Memorial Hospital
		J. Philip Kuebler	Ph: 614-566-3275
	Oregon
	St. Charles Mercy Hospital
		Rex B Mowat	Ph: 517-265-0116
	Toledo Clinic - Oregon
		Rex B Mowat	Ph: 517-265-0116
	Portsmouth
	Southern Ohio Medical Center Cancer Center
		J. Philip Kuebler	Ph: 614-566-3275
	Springfield
	Community Hospital of Springfield and Clark County
		J. Philip Kuebler	Ph: 614-566-3275
	Sylvania
	Flower Hospital Cancer Center
		Rex B Mowat	Ph: 517-265-0116
	Tiffin
	Mercy Hospital of Tiffin
		Rex B Mowat	Ph: 517-265-0116
	Toledo
	CCOP - Toledo Community Hospital
		Rex B Mowat	Ph: 517-265-0116
	St. Anne Mercy Hospital
		Rex B Mowat	Ph: 517-265-0116
	St. Vincent Mercy Medical Center
		Rex B Mowat	Ph: 517-265-0116
	Toledo Clinic, Incorporated - Main Clinic
		Rex B Mowat	Ph: 517-265-0116
	Toledo Hospital
		Rex B Mowat	Ph: 517-265-0116
	University of Toledo Medical Center
		Rex B Mowat	Ph: 517-265-0116
	Troy
	UVMC Cancer Care Center at Upper Valley Medical Center
		Howard M. Gross	Ph: 317-783-8918
	Wauseon
	Fulton County Health Center
		Rex B Mowat	Ph: 517-265-0116
	Westerville
	Mount Carmel St. Ann's Cancer Center
		J. Philip Kuebler	Ph: 614-566-3275
	Xenia
	Ruth G. McMillan Cancer Center at Greene Memorial Hospital
		Howard M. Gross	Ph: 317-783-8918
	Zanesville
	Genesis - Good Samaritan Hospital
		J. Philip Kuebler	Ph: 614-566-3275
Oklahoma
	Oklahoma City
	Oklahoma University Cancer Institute
		George B Selby	Ph: 405-271-4272
			Email: julie-traylor@ouhsc.edu
	Tulsa
	Natalie Warren Bryant Cancer Center at St. Francis Hospital
		Joseph P. Lynch	Ph: 918-494-2200
Oregon
	Glesham
	Legacy Mount Hood Medical Center
		Jacqueline Vuky	Ph: 503-299-6500
	Portland
	Legacy Emanuel Hospital and Health Center and Children's Hospital
		Jacqueline Vuky	Ph: 503-299-6500
	Legacy Good Samaritan Hospital & Comprehensive Cancer Center
		Jacqueline Vuky	Ph: 503-299-6500
	Tualatin
	Legacy Meridian Park Hospital
		Jacqueline Vuky	Ph: 503-299-6500
Pennsylvania
	Abington
	Rosenfeld Cancer Center at Abington Memorial Hospital
		Willard G. Andrews	Ph: 215-481-2402
	Allentown
	Morgan Cancer Center at Lehigh Valley Hospital - Cedar Crest
		Eliot Lawrence Friedman	Ph: 610-402-2273
	Sayre
	Guthrie Cancer Center at Guthrie Clinic Sayre
		Bradley W Lash	Ph: 800-836-0388
	West Reading
	McGlinn Family Regional Cancer Center at Reading Hospital and Medical Center
		Terrence P. Cescon	Ph: 610-988-9323
South Dakota
	Sioux Falls
	Avera Cancer Institute
		Addison R Tolentino	Ph: 800-657-4377
			Email: Jan.Healy@avera.org
	Sanford Cancer Center at Sanford USD Medical Center
		Miroslaw A Mazurczak	Ph: 605-328-1367
		Miroslaw A Mazurczak	Ph: 605-328-1367
Tennessee
	Chattanooga
	Erlanger Cancer Center at Erlanger Hospital - Baroness
		Larry L. Schlabach	Ph: 423-778-6947
	Nashville
	Vanderbilt-Ingram Cancer Center
		Dana B Cardin	Ph: 800-811-8480
Texas
	Amarillo
	Harrington Cancer Center
		Stewart Allen Sharp	Ph: 806-359-4673
			Email: ryokubaitis@harringtoncc.org
	Lubbock
	Texas Tech University Health Sciences Center
		Fred L Hardwicke	Ph: 806-775-8590
			Email: terry.fountain@umchealthsystem.com
Utah
	Salt Lake City
	Huntsman Cancer Institute at University of Utah
		Glynn W Gilcrease	Ph: 801-581-4477
			Email: clinical.trials@hci.utah.edu
Virginia
	Charlottesville
	Martha Jefferson Hospital Cancer Care Center
		J. Mark Prichard	Ph: 434-654-8400
	Danville
	Danville Regional Medical Center
		Timothy W. Brotherton	Ph: 434-793-0044
	Fredericksburg
	Fredericksburg Oncology Inc
		Rex B Mowat	Ph: 517-265-0116
Washington
	Anacortes
	Cancer Care Center at Island Hogs
		Gary E Goodman	Ph: 206-386-2323
			Email: patra.grevstad@swedish.org
	Bellingham
	St. Joseph Cancer Center
		Gary E Goodman	Ph: 206-386-2323
			Email: patra.grevstad@swedish.org
	Bremerton
	Olympic Hematology and Oncology
		Gary E Goodman	Ph: 206-386-2323
			Email: patra.grevstad@swedish.org
	Burien
	Highline Medical Center Cancer Center
		Gary E Goodman	Ph: 206-386-2323
			Email: patra.grevstad@swedish.org
	Edmonds
	Swedish Cancer Institute at Stevens Hospital
		Gary E Goodman	Ph: 206-386-2323
			Email: patra.grevstad@swedish.org
	Issaquah
	Swedish Medical Center - Issaquah Campus
		Gary E Goodman	Ph: 206-386-2323
			Email: patra.grevstad@swedish.org
	Kennewick
	Columbia Basin Hematology
		Gary E Goodman	Ph: 206-386-2323
			Email: patra.grevstad@swedish.org
	Mount Vernon
	Skagit Valley Hospital Cancer Care Center
		Gary E Goodman	Ph: 206-386-2323
			Email: patra.grevstad@swedish.org
	Poulsbo
	Harrison Poulsbo Hematology and Onocology
		Gary E Goodman	Ph: 206-386-2323
			Email: patra.grevstad@swedish.org
	Seattle
	Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium
		Gary E Goodman	Ph: 206-386-2323
			Email: patra.grevstad@swedish.org
	Group Health Central Hospital
		Gary E Goodman	Ph: 206-386-2323
			Email: patra.grevstad@swedish.org
	Harborview Medical Center
		Gary E Goodman	Ph: 206-386-2323
			Email: patra.grevstad@swedish.org
	Minor and James Medical, PLLC
		Gary E Goodman	Ph: 206-386-2323
			Email: patra.grevstad@swedish.org
	Swedish Cancer Institute at Swedish Medical Center - First Hill Campus
		Gary E Goodman	Ph: 206-386-2323
			Email: patra.grevstad@swedish.org
	University Cancer Center at University of Washington Medical Center
		Gary E Goodman	Ph: 206-386-2323
			Email: patra.grevstad@swedish.org
	Sedro-Woolley
	North Puget Oncology at United General Hospital
		Gary E Goodman	Ph: 206-386-2323
			Email: patra.grevstad@swedish.org
	Spokane
	Cancer Care Northwest - Spokane South
		Gary E Goodman	Ph: 206-386-2323
			Email: patra.grevstad@swedish.org
	Evergreen Hematology and Oncology, PS
		Gary E Goodman	Ph: 206-386-2323
			Email: patra.grevstad@swedish.org
	Vancouver
	Legacy Salmon Creek Medical Center
		Jacqueline Vuky	Ph: 503-299-6500
	Wenatchee
	Wenatchee Valley Medical Center
		Gary E Goodman	Ph: 206-386-2323
			Email: patra.grevstad@swedish.org
West Virginia
	Charleston
	West Virginia University Medical School - Charleston
		Steven J. Jubelirer	Ph: 304-388-9944
Wisconsin
	Appleton
	Fox Valley Hematology and Oncology - East Grant Street
		Avi Bar-Lev	Ph: 920-749-1171
	Chippewa Falls
	Marshfield Clinic - Chippewa Center
		Elena N Theodosiou	Ph: 715-389-4457
	Eau Claire
	Center for Cancer Treatment & Prevention at Sacred Heart Hospital
		Elena N Theodosiou	Ph: 715-389-4457
	Marshfield Clinic Cancer Care at Regional Cancer Center
		Elena N Theodosiou	Ph: 715-389-4457
	La Crosse
	Gundersen Lutheran Center for Cancer and Blood
		Kurt Oettel	Ph: 608-775-2385
			Email: cancerctr@gundluth.org
	Ladysmith
	Marshfield Clinic - Ladysmith Center
		Elena N Theodosiou	Ph: 715-389-4457
	Madison
	Dean Hematology & Oncology Clinic
		Amit Sanyal	Ph: 608-410-2700
	Marshfield
	Marshfield Clinic - Marshfield Center
		Elena N Theodosiou	Ph: 715-389-4457
	Saint Joseph's Hospital
		Elena N Theodosiou	Ph: 715-389-4457
	Minocqua
	Marshfield Clinic - Lakeland Center
		Elena N Theodosiou	Ph: 715-389-4457
	Mukwonago
	D.N. Greenwald Center
		Timothy R Wassenaar	Ph: 262-928-7632
	New Richmond
	Cancer Center of Western Wisconsin
		Joseph W Leach	Ph: 952-993-1517
			Email: MMCCOP@parknicollet.com
	Oconomowoc
	Regional Cancer Center at Oconomowoc Memorial Hospital
		Timothy R Wassenaar	Ph: 262-928-7632
	Rhinelander
	Ministry Medical Group at Saint Mary's Hospital
		Elena N Theodosiou	Ph: 715-389-4457
		Elena N Theodosiou	Ph: 715-389-4457
	Rice Lake
	Marshfield Clinic - Indianhead Center
		Elena N Theodosiou	Ph: 715-389-4457
	Stevens Point
	Marshfield Clinic at Saint Michael's Hospital
		Elena N Theodosiou	Ph: 715-389-4457
	Saint Michael's Hospital Cancer Center
		Elena N Theodosiou	Ph: 715-389-4457
	Waukesha
	Waukesha Memorial Hospital Regional Cancer Center
		Timothy R Wassenaar	Ph: 262-928-7632
	Wausau
	Marshfield Clinic - Wausau Center
		Elena N Theodosiou	Ph: 715-389-4457
	Weston
	Diagnostic and Treatment Center
		Elena N Theodosiou	Ph: 715-389-4457
	Marshfield Clinic - Weston Center
		Elena N Theodosiou	Ph: 715-389-4457
	Ministry Saint Clare's Hospital
		Elena N Theodosiou	Ph: 715-389-4457
	Wisconsin Rapids
	Marshfield Clinic - Wisconsin Rapids Center
		Elena N Theodosiou	Ph: 715-389-4457
Wyoming
	Casper
	Rocky Mountain Oncology
		Benjamin Thomas Marchello	Ph: 800-648-6274
	Sheridan
	Welch Cancer Center at Sheridan Memorial Hospital
		Benjamin Thomas Marchello	Ph: 800-648-6274