Study of Blood Samples From Newborns With Down Syndrome
Trial Sites
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Basic Trial Information
Trial Description
Summary
Further Trial Information
Eligibility Criteria
Trial Contact Information
| Phase | Type | Status | Age | Sponsor | Protocol IDs |
|---|---|---|---|---|---|
| No phase specified | Biomarker/Laboratory analysis | Active | Under 90 days at diagnosis | NCI, Other | CDR0000636115 COG-AAML08B1, AAML08B1, NCT00959283 |
Summary
RATIONALE: Studying the genes expressed in samples of blood from patients with Down syndrome may help doctors identify biomarkers related to cancer.
PURPOSE: This research study is looking at blood samples from newborns with Down syndrome.
Further Study Information
OBJECTIVES:
- To further our biological understanding of the natural history of transient myeloproliferative disorder (TMD) and its relationship to subsequent leukemia by facilitating the development of a TMD cell and protein bank, and repository of DNA/RNA from megakaryoblasts for future biological studies.
- To investigate the biology of TMD molecular changes associated with resolution of TMD or its conversion to acute myeloid leukemia within each mortality-risk group by conducting GATA1 mutational analyses, hematopoiesis clonality studies, assessment of RAS mutations, and genomic instability studies using glycophorin A assays.
- To determine if high-resolution microarray genomic analysis of TMD blasts (using Affymetrix SNP Genechip technology to assess gene expression, copy number variation, and loss of heterozygosity) can predict the development of subsequent leukemia.
- To determine the relationship of minimal residual disease (monitored by peripheral blood flow cytometry and GATA1 mutational studies) to clinical remission status and development of subsequent leukemia within each mortality-risk group of TMD patients.
- To evaluate the relationship between karyotype (including FISH analysis) and subsequent leukemia in TMD patients.
- To examine pharmacogenetics and in vitro drug sensitivity to cytarabine (MTT assay) in blasts from TMD patients.
- To examine the relationship of functional polymorphisms in Phase I and Phase II drug detoxification genes, DNA repair, and DNA synthesis pathways that may modify susceptibility to leukemia and outcome in TMD patients.
- To determine the relationship between fibrosis-associated serum factors (e.g., platelet-derived growth factor, transforming growth factor beta, N-terminal peptide of III procollagen, type IV collagen, and hyaluronic acid) and event-free survival.
OUTLINE: This is a multicenter study.
Patients undergo peripheral blood collection periodically for biomarker analysis. Samples are analyzed for GATA1 mutations by real-time PCR, polymorphisms, cytogenetics, - and K-RAS mutations, gene expression, drug sensitivity patterns, and minimal residual disease by flow cytometry.
Patients are followed up periodically for 5 years.
Eligibility Criteria
DISEASE CHARACTERISTICS:
- Diagnosis of transient myeloproliferative disorder (TMD) at < 90 days of age and meeting 1 of the following criteria:
- A diagnosis of Down syndrome or Down syndrome mosaicism AND non-erythroid and non-lymphoid blasts (any amount) in the peripheral blood verified with a second sample
- Patients with typical physical characteristics of Down syndrome are allowed before cytogenetic or FISH confirmation of the diagnosis
- Trisomy 21-positive leukemic blasts documented by biopsy of any organ (including > 5% non-erythroid/non-lymphoid blasts documented by bone marrow aspirate or biopsy)
- Infants with isolated trisomy 21 positivity identified only in the leukemic blasts are allowed
- Institutional immunophenotype characterization is required for study enrollment
PATIENT CHARACTERISTICS:
- Not specified
PRIOR CONCURRENT THERAPY:
- Not specified
Trial Lead Organizations/Sponsors
Children's Oncology Group
National Cancer Institute| April Deon Sorrell |  | Principal Investigator |
Trial Sites
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| U.S.A. | |||
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| Alabama | |||
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| Birmingham | |||
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| Children's Hospital of Alabama at University of Alabama at Birmingham | |||
| Alyssa T Reddy | Ph: 205-934-0309 | ||
| Mobile | |||
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| University of South Alabama Mitchell Cancer Institute | |||
| Felicia L Wilson | Ph: 251-665-8000 | ||
| Arizona | |||
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| Phoenix | |||
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| Phoenix Children's Hospital | |||
| Jessica Boklan | Ph: 602-546-0920 | ||
| Arkansas | |||
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| Little Rock | |||
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| Arkansas Cancer Research Center at University of Arkansas for Medical Sciences | |||
| David L Becton | Ph: 501-364-7373 | ||
| California | |||
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| Downey | |||
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| Southern California Permanente Medical Group | |||
| Robert M Cooper | Ph: 626-564-3455 | ||
| Loma Linda | |||
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| Loma Linda University Cancer Institute at Loma Linda University Medical Center | |||
| Antranik A Bedros | Ph: 909-558-3375 | ||
| Long Beach | |||
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| Jonathan Jaques Children's Cancer Center at Miller Children's Hospital | |||
| Amanda M Termuhlen | Ph: 562-933-5437 | ||
| Los Angeles | |||
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| Childrens Hospital Los Angeles | |||
| Leo Mascarenhas | Ph: 323-361-4110 | ||
| Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center | |||
| Carole H Hurvitz | Ph: 310-423-8965 | ||
| Madera | |||
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| Children's Hospital Central California | |||
| Vonda L Crouse | Ph: 866-353-5437 | ||
| Oakland | |||
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| Children's Hospital and Research Center Oakland | |||
| Carla B Golden | Ph: 510-450-7600 | ||
| Orange | |||
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| Children's Hospital of Orange County | |||
| Violet Shen | Ph: 714-997-3000 | ||
| Palo Alto | |||
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| Lucile Packard Children's Hospital at Stanford University Medical Center | |||
| Neyssa M Marina | Ph: 650-498-7061 | ||
| Email: clinicaltrials@med.stanford.edu | |||
| Sacramento | |||
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| University of California Davis Cancer Center | |||
| Jay Michael S Balagtas | Ph: 916-734-3089 | ||
| San Diego | |||
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| Rady Children's Hospital - San Diego | |||
| William D Roberts | Ph: 858-966-5934 | ||
| San Francisco | |||
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| UCSF Helen Diller Family Comprehensive Cancer Center | |||
| Mignon Loh | Ph: 877-827-3222 | ||
| Colorado | |||
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| Aurora | |||
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| Children's Hospital Colorado Center for Cancer and Blood Disorders | |||
| Kelly W Maloney | Ph: 720-777-6672 | ||
| Denver | |||
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| Presbyterian - St. Luke's Medical Center | |||
| Jennifer J Clark | Ph: 866-775-6246 | ||
| Connecticut | |||
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| Hartford | |||
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| Connecticut Children's Medical Center | |||
| Michael S Isakoff | Ph: 860-545-9981 | ||
| New Haven | |||
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| Yale Cancer Center | |||
| Nina S Kadan-Lottick | Ph: 203-785-5702 | ||
| Delaware | |||
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| Wilmington | |||
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| Alfred I. duPont Hospital for Children | |||
| Christopher N Frantz | Ph: 302-651-5755 | ||
| District of Columbia | |||
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| Washington | |||
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| Lombardi Comprehensive Cancer Center at Georgetown University Medical Center | |||
| Aziza T Shad | Ph: 202-444-0381 | ||
| Florida | |||
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| Fort Myers | |||
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| Lee Cancer Care of Lee Memorial Health System | |||
| Emad K Salman | Ph: 239-343-5333 | ||
| Gainesville | |||
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| University of Florida Shands Cancer Center | |||
| William B Slayton | Ph: 352-273-8675 | ||
| Email: trials@cancer.ufl.edu | |||
| Hollywood | |||
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| Joe DiMaggio Children's Hospital | |||
| Iftikhar Hanif | Ph: 954-265-2234 | ||
| Jacksonville | |||
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| Nemours Children's Clinic | |||
| Eric S Sandler | Ph: 904-697-3529 | ||
| Orlando | |||
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| Florida Hospital Cancer Institute at Florida Hospital Orlando | |||
| Clifford A Selsky | Ph: 407-303-5623 | ||
| M.D. Anderson Cancer Center at Orlando | |||
| Vincent F Giusti | Ph: 321-841-7246 | ||
| Nemours Children's Clinic - Orlando | |||
| Ramamoorthy Nagasubramanian | Ph: 407-650-7150 | ||
| Pensacola | |||
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| Nemours Children's Clinic - Pensacola | |||
| Jeffrey H Schwartz | Ph: 904-697-3529 | ||
| Saint Petersburg | |||
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| All Children's Hospital | |||
| Gregory A Hale | Ph: 727-767-2423 | ||
| Email: HamblinF@allkids.org | |||
| Tampa | |||
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| St. Joseph's Children's Hospital of Tampa | |||
| Hardeo K Panchoosingh | Ph: 800-882-4123 | ||
| West Palm Beach | |||
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| Kaplan Cancer Center at St. Mary's Medical Center | |||
| Narayana Gowda | Ph: 888-823-5923 | ||
| Email: ctsucontact@westat.com | |||
| Georgia | |||
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| Atlanta | |||
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| AFLAC Cancer Center and Blood Disorders Service of Children's Healthcare of Atlanta - Egleston Campus | |||
| Howard M Katzenstein | Ph: 888-785-1112 | ||
| Savannah | |||
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| Curtis and Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center | |||
| J. Martin Johnston | Ph: 912-350-8568 | ||
| Hawaii | |||
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| Honolulu | |||
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| Cancer Research Center of Hawaii | |||
| Robert W Wilkinson | Ph: 808-983-6090 | ||
| Illinois | |||
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| Chicago | |||
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| Ann and Robert H. Lurie Children's Hospital of Chicago | |||
| David O Walterhouse | Ph: 773-880-4562 | ||
| University of Chicago Cancer Research Center | |||
| Susan L Cohn | Ph: 773-834-7424 | ||
| University of Illinois Cancer Center | |||
| Mary L Schmidt | Ph: 312-355-3046 | ||
| Oak Lawn | |||
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| Keyser Family Cancer Center at Advocate Hope Children's Hospital | |||
| Sharad N Salvi | Ph: 847-723-7570 | ||
| Springfield | |||
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| Simmons Cooper Cancer Institute | |||
| Gregory P Brandt | Ph: 217-545-7929 | ||
| Indiana | |||
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| Indianapolis | |||
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| Riley's Children Cancer Center at Riley Hospital for Children | |||
| Robert J Fallon | Ph: 317-274-2552 | ||
| St. Vincent Indianapolis Hospital | |||
| Bassem I Razzouk | Ph: 317-338-2194 | ||
| Iowa | |||
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| Des Moines | |||
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| Blank Children's Hospital | |||
| Wendy L Woods-Swafford | Ph: 888-823-5923 | ||
| Email: ctsucontact@westat.com | |||
| Iowa City | |||
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| Holden Comprehensive Cancer Center at University of Iowa | |||
| Raymond Tannous | Ph: 800-237-1225 | ||
| Kentucky | |||
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| Lexington | |||
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| University of Kentucky Chandler Medical Center | |||
| Martha F Greenwood | Ph: 859-257-3379 | ||
| Louisville | |||
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| Kosair Children's Hospital | |||
| Salvatore J Bertolone | Ph: 866-530-5516 | ||
| Louisiana | |||
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| New Orleans | |||
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| Children's Hospital of New Orleans | |||
| Lolie C Yu | Ph: 504-894-5377 | ||
| Tulane Cancer Center at Tulane University Hospital and Clinic | |||
| Tammuella C Singleton | Ph: 504-988-6121 | ||
| Maine | |||
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| Bangor | |||
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| CancerCare of Maine at Eastern Maine Medical Center | |||
| Judith B Allen | Ph: 207-973-4274 | ||
| Maryland | |||
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| Baltimore | |||
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| Alvin and Lois Lapidus Cancer Institute at Sinai Hospital | |||
| Joseph M Wiley | Ph: 410-601-6120 | ||
| Email: pridgely@lifebridgehealth.org | |||
| Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | |||
| Robert J Arceci | Ph: 602-546-0920 | ||
| Email: jhcccro@jhmi.edu | |||
| Bethesda | |||
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| National Naval Medical Center | |||
| Anne B Warwick | Ph: 301-319-2100 | ||
| Massachusetts | |||
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| Boston | |||
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| Floating Hospital for Children at Tufts - New England Medical Center | |||
| Johannes E Wolff | Ph: 617-636-5000 | ||
| Email: ContactUsCancerCenter@TuftsMedicalCenter.org | |||
| Michigan | |||
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| Ann Arbor | |||
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| C.S. Mott Children's Hospital at University of Michigan Medical Center | |||
| Rajen Mody | Ph: 800-865-1125 | ||
| Detroit | |||
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| Van Elslander Cancer Center at St. John Hospital and Medical Center | |||
| Hadi Sawaf | Ph: 313-343-3166 | ||
| Wayne State University | |||
| Jeffrey W Taub | Ph: 313-576-9363 | ||
| Flint | |||
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| Hurley Medical Center | |||
| Susumu Inoue | Ph: 888-606-6556 | ||
| Grand Rapids | |||
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| Helen DeVos Children's Hospital at Spectrum Health | |||
| David S Dickens | Ph: 616-267-1925 | ||
| Kalamazoo | |||
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| Bronson Methodist Hospital | |||
| Jeffrey S Lobel | Ph: 800-227-2345 | ||
| Lansing | |||
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| Breslin Cancer Center at Ingham Regional Medical Center | |||
| Renuka Gera | Ph: 517-334-2765 | ||
| Minnesota | |||
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| Minneapolis | |||
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| Children's Hospitals and Clinics of Minnesota - Minneapolis | |||
| Bruce C Bostrom | Ph: 612-813-5193 | ||
| Rochester | |||
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| Mayo Clinic Cancer Center | |||
| Carola A. S. Arndt | Ph: 507-538-7623 | ||
| Mississippi | |||
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| Jackson | |||
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| University of Mississippi Cancer Clinic | |||
| Gail C Megason | Ph: 601-815-6700 | ||
| Missouri | |||
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| Columbia | |||
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| Ellis Fischel Cancer Center at University of Missouri - Columbia | |||
| Thomas W Loew | Ph: 573-882-7440 | ||
| Kansas City | |||
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| Children's Mercy Hospital | |||
| Maxine L Hetherington | Ph: 816-234-3265 | ||
| Saint Louis | |||
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| Cardinal Glennon Children's Hospital | |||
| William S Ferguson | Ph: 314-268-4000 | ||
| David C. Pratt Cancer Center at St. John's Mercy | |||
| Bethany G. Sleckman | Ph: 913-948-5588 | ||
| Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis | |||
| Robert J Hayashi | Ph: 800-600-3606 | ||
| Email: info@siteman.wustl.edu | |||
| Nebraska | |||
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| Omaha | |||
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| Children's Hospital | |||
| Minnie Abromowitch | Ph: 402-955-3949 | ||
| UNMC Eppley Cancer Center at the University of Nebraska Medical Center | |||
| Peter F Coccia | Ph: 800-999-5465 | ||
| Nevada | |||
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| Las Vegas | |||
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| CCOP - Nevada Cancer Research Foundation | |||
| Jonathan Bernstein | Ph: 702-384-0013 | ||
| New Hampshire | |||
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| Lebanon | |||
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| Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center | |||
| Sara Chaffee | Ph: 800-639-6918 | ||
| Email: cancer.research.nurse@dartmouth.edu | |||
| New Jersey | |||
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| Hackensack | |||
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| Hackensack University Medical Center Cancer Center | |||
| Burton E Appel | Ph: 201-996-2879 | ||
| Livingston | |||
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| St. Barnabas Medical Center Cancer Center | |||
| Stacey Rifkin-Zenenberg | Ph: 973-926-7230 | ||
| Morristown | |||
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| Carol G. Simon Cancer Center at Morristown Memorial Hospital | |||
| Steven L Halpern | Ph: 973-971-5900 | ||
| New Brunswick | |||
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| Saint Peter's University Hospital | |||
| Stanley Calderwood | Ph: 732-745-8600ext6163 | ||
| Email: kcovert@saintpetersuh.com | |||
| Newark | |||
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| Newark Beth Israel Medical Center | |||
| Peri Kamalakar | Ph: 973-926-7230 | ||
| Paterson | |||
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| St. Joseph's Hospital and Medical Center | |||
| Mary A Bonilla | Ph: 973-754-2909 | ||
| New Mexico | |||
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| Albuquerque | |||
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| University of New Mexico Cancer Center | |||
| Koh B Boayue | Ph: 505-272-6972 | ||
| New York | |||
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| Albany | |||
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| Albany Medical Center Hospital | |||
| Vikramjit S Kanwar | Ph: 518-262-3368 | ||
| Bronx | |||
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| Montefiore Medical Center | |||
| Rosanna J Ricafort | Ph: 718-904-2730 | ||
| Email: aecc@aecom.yu.edu | |||
| Buffalo | |||
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| Roswell Park Cancer Institute | |||
| Meghan A Higman | Ph: 877-275-7724 | ||
| Mineola | |||
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| Winthrop University Hospital | |||
| Mark E Weinblatt | Ph: 866-946-8476 | ||
| New Hyde Park | |||
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| Schneider Children's Hospital | |||
| Arlene S Redner | Ph: 718-470-3470 | ||
| New York | |||
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| Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center | |||
| Alice Lee | Ph: 212-305-8615 | ||
| New York University Medical Center | |||
| Elizabeth A Raetz | Ph: 212-263-4434 | ||
| Email: prmc.coordinator@nyumc.org | |||
| Rochester | |||
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| James P. Wilmot Cancer Center at University of Rochester Medical Center | |||
| Lisa R Hackney | Ph: 585-275-5830 | ||
| Stony Brook | |||
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| Stony Brook University Cancer Center | |||
| Robert I Parker | Ph: 800-862-2215 | ||
| Syracuse | |||
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| SUNY Upstate Medical University Hospital | |||
| Karol H Kerr | Ph: 315-464-5476 | ||
| North Carolina | |||
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| Asheville | |||
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| Mission Hospitals - Memorial Campus | |||
| Orren Beaty | Ph: 828-213-4150 | ||
| Chapel Hill | |||
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| Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill | |||
| Stuart H Gold | Ph: 877-668-0683 | ||
| Charlotte | |||
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| Blumenthal Cancer Center at Carolinas Medical Center | |||
| Joel A Kaplan | Ph: 704-355-2884 | ||
| Presbyterian Cancer Center at Presbyterian Hospital | |||
| Paulette C Bryant | Ph: 704-384-5369 | ||
| Durham | |||
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| Duke Cancer Institute | |||
| Susan G Kreissman | Ph: 888-275-3853 | ||
| Greenville | |||
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| Leo W. Jenkins Cancer Center at ECU Medical School | |||
| Mauro Grossi | Ph: 252-744-2161 | ||
| Winston-Salem | |||
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| Wake Forest University Comprehensive Cancer Center | |||
| Thomas W McLean | Ph: 336-713-6771 | ||
| North Dakota | |||
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| Fargo | |||
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| Roger Maris Cancer Center at MeritCare Hospital | |||
| Nathan L Kobrinsky | Ph: 701-234-6161 | ||
| Ohio | |||
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| Akron | |||
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| Akron Children's Hospital | |||
| Steven J Kuerbitz | Ph: 330-543-3193 | ||
| Cincinnati | |||
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| Cincinnati Children's Hospital Medical Center | |||
| John P Perentesis | Ph: 513-636-2799 | ||
| Cleveland | |||
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| Cleveland Clinic Taussig Cancer Center | |||
| Tanya M Tekautz | Ph: 866-223-8100 | ||
| Seidman Cancer Center at University Hospitals/Case Medical Center | |||
| Yousif (Joe) H Matloub | Ph: 216-844-5437 | ||
| Columbus | |||
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| Nationwide Children's Hospital | |||
| Laura T Martin | Ph: 614-722-2708 | ||
| Dayton | |||
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| Dayton Children's - Dayton | |||
| Emmett H Broxson | Ph: 800-228-4055 | ||
| Toledo | |||
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| Mercy Children's Hospital | |||
| Rama Jasty | Ph: 419-251-8210 | ||
| Toledo Hospital | |||
| Dagmar T Stein | Ph: 419-824-1842 | ||
| Oklahoma | |||
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| Oklahoma City | |||
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| Oklahoma University Cancer Institute | |||
| Rene Y McNall-Knapp | Ph: 405-271-4272 | ||
| Email: julie-traylor@ouhsc.edu | |||
| Tulsa | |||
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| Natalie Warren Bryant Cancer Center at St. Francis Hospital | |||
| Gregory B Kirkpatrick | Ph: 918-494-2200 | ||
| Oregon | |||
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| Portland | |||
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| Knight Cancer Institute at Oregon Health and Science University | |||
| Bill H Chang | Ph: 503-494-1080 | ||
| Email: trials@ohsu.edu | |||
| Legacy Emanuel Children's Hospital | |||
| Janice F Olson | Ph: 503-413-2560 | ||
| Pennsylvania | |||
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| Danville | |||
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| Geisinger Cancer Institute at Geisinger Health | |||
| Jeffrey S Taylor | Ph: 570-271-5251 | ||
| Hershey | |||
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| Penn State Children's Hospital | |||
| Lisa M McGregor | Ph: 717-531-6012 | ||
| Philadelphia | |||
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| Children's Hospital of Philadelphia | |||
| Richard Aplenc | Ph: 215-590-2810 | ||
| Pittsburgh | |||
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| Children's Hospital of Pittsburgh of UPMC | |||
| Arthur K Ritchey | Ph: 412-692-5573 | ||
| Rhode Island | |||
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| Providence | |||
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| Rhode Island Hospital Comprehensive Cancer Center | |||
| Cindy L Schwartz | Ph: 401-444-1488 | ||
| South Carolina | |||
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| Charleston | |||
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| Hollings Cancer Center at Medical University of South Carolina | |||
| Jacqueline M Kraveka | Ph: 843-792-9321 | ||
| Columbia | |||
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| Palmetto Health South Carolina Cancer Center | |||
| Ronnie W. Neuberg | Ph: 803-434-3680 | ||
| South Dakota | |||
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| Sioux Falls | |||
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| Sanford Cancer Center at Sanford USD Medical Center | |||
| Kayelyn J Wagner | Ph: 605-328-1367 | ||
| Tennessee | |||
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| Knoxville | |||
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| East Tennessee Children's Hospital | |||
| Ray C Pais | Ph: 865-541-8266 | ||
| Memphis | |||
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| St. Jude Children's Research Hospital | |||
| Wayne L Furman | Ph: 901-595-4644 | ||
| Nashville | |||
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| Vanderbilt-Ingram Cancer Center | |||
| Haydar A Frangoul | Ph: 800-811-8480 | ||
| Texas | |||
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| Amarillo | |||
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| Texas Tech University Health Sciences Center School of Medicine - Amarillo | |||
| Osvaldo Regueira | Ph: 806-354-5411 | ||
| Corpus Christi | |||
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| Driscoll Children's Hospital | |||
| M. Cris Johnson | Ph: 361-694-5311 | ||
| Dallas | |||
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| Medical City Dallas Hospital | |||
| Carl Lenarsky | Ph: 972-566-5588 | ||
| Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas | |||
| Naomi J Winick | Ph: 214-648-7097 | ||
| Fort Worth | |||
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| Cook Children's Medical Center - Fort Worth | |||
| Mary Meaghan P Granger | Ph: 682-885-2103 | ||
| Houston | |||
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| Dan L. Duncan Cancer Center at Baylor College of Medicine | |||
| Karen R Rabin | Ph: 713-798-1354 | ||
| Email: burton@bcm.edu | |||
| San Antonio | |||
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| University of Texas Health Science Center at San Antonio | |||
| Anne-Marie R Langevin | Ph: 210-567-0653 | ||
| Email: che@uthscsa.edu | |||
| Utah | |||
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| Salt Lake City | |||
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| Primary Children's Medical Center | |||
| Phillip E Barnette | Ph: 801-585-5270 | ||
| Virginia | |||
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| Charlottesville | |||
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| University of Virginia Cancer Center | |||
| Kimberly P Dunsmore | Ph: 434-243-6143 | ||
| Falls Church | |||
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| Inova Fairfax Hospital | |||
| Marshall A Schorin | Ph: 703-208-6650 | ||
| Norfolk | |||
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| Children's Hospital of The King's Daughters | |||
| Eric J Lowe | Ph: 757-668-7243 | ||
| Roanoke | |||
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| Carilion Medical Center for Children at Roanoke Community Hospital | |||
| Mandy M Atkinson | Ph: 540-981-7376 | ||
| Washington | |||
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| Seattle | |||
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| Children's Hospital and Regional Medical Center - Seattle | |||
| Jessica A Pollard | Ph: 866-987-2000 | ||
| Spokane | |||
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| Providence Cancer Center at Sacred Heart Medical Center | |||
| Judy L Felgenhauer | Ph: 800-228-6618 | ||
| Email: HopeBeginsHere@providence.org | |||
| Tacoma | |||
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| Mary Bridge Children's Hospital and Health Center - Tacoma | |||
| Robert G Irwin | Ph: 888-823-5923 | ||
| Email: ctsucontact@westat.com | |||
| West Virginia | |||
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| Charleston | |||
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| West Virginia University Medical School - Charleston | |||
| Allen R Chauvenet | Ph: 304-388-9944 | ||
| Wisconsin | |||
|
|||
| Green Bay | |||
|
|||
| St. Vincent Hospital Regional Cancer Center | |||
| John R Hill | Ph: 920-433-8889 | ||
| Milwaukee | |||
|
|||
| Midwest Children's Cancer Center at Children's Hospital of Wisconsin | |||
| Michael E Kelly | Ph: 414-805-4380 | ||
| Australia | |||
|
|||
| Victoria | |||
|
|||
| Parkville | |||
|
|||
| Royal Children's Hospital | |||
| David M Ashley | |||
| Email: crdo.info@mcri.edu.au | |||
| Western Australia | |||
|
|||
| Perth | |||
|
|||
| Princess Margaret Hospital for Children | |||
| Catherine H Cole | Ph: (08) 9340 8330 | ||
| Email: admin@childcancerresearch.com.au | |||
| Canada | |||
|
|||
| British Columbia | |||
|
|||
| Vancouver | |||
|
|||
| Children's and Women's Hospital of British Columbia | |||
| Caron Strahlendorf | Ph: 604-875-2345ext6477 | ||
| Manitoba | |||
|
|||
| Winnipeg | |||
|
|||
| CancerCare Manitoba | |||
| Rochelle A Yanofsky | Ph: 866-561-1026 | ||
| Email: CIO_Web@cancercare.mb.ca | |||
| Newfoundland and Labrador | |||
|
|||
| Saint John's | |||
|
|||
| Janeway Children's Health and Rehabilitation Centre | |||
| John P Hand | Ph: 866-722-1126 | ||
| Nova Scotia | |||
|
|||
| Halifax | |||
|
|||
| IWK Health Centre | |||
| Margaret C Yhap | Ph: 902-470-8394 | ||
| Ontario | |||
|
|||
| Hamilton | |||
|
|||
| McMaster Children's Hospital at Hamilton Health Sciences | |||
| Carol Portwine | Ph: 905-521-2100ext74595 | ||
| Kingston | |||
|
|||
| Cancer Centre of Southeastern Ontario at Kingston General Hospital | |||
| Mariana P Silva | Ph: 613-544-2630 | ||
| London | |||
|
|||
| Children's Hospital of Western Ontario | |||
| Anne E Cairney | Ph: 519-685-8306 | ||
| Ottawa | |||
|
|||
| Children's Hospital of Eastern Ontario | |||
| Jacqueline M Halton | Ph: 613-738-3931 | ||
| Toronto | |||
|
|||
| Hospital for Sick Children | |||
| Ronald M Grant | Ph: 416-813-7654ext2027 | ||
| Email: jason.mcguire@sickkids.ca | |||
| Quebec | |||
|
|||
| Montreal | |||
|
|||
| Hopital Sainte Justine | |||
| Yvan Samson | Ph: 514-345-4931 | ||
| Montreal Children's Hospital at McGill University Health Center | |||
| Sharon B Abish | Ph: 514-412-4445 | ||
| Email: info@thechildren.com | |||
| Ste-Foy | |||
|
|||
| Centre de Recherche du Centre Hospitalier de l'Universite Laval | |||
| Bruno Michon | Ph: 418-525-4444 | ||
Link to the current ClinicalTrials.gov record.
NLM Identifer NCT00959283
Information obtained from ClinicalTrials.gov on November 22, 2012
Note: Information about this trial is from the ClinicalTrials.gov database. The versions designated for health professionals and patients contain
the same text. Minor
changes may be made to the ClinicalTrials.gov record to standardize the names of study sponsors, sites, and
contacts. Cancer.gov only lists sites that are recruiting patients for active trials, whereas ClinicalTrials.gov lists all sites for all trials. Questions and comments regarding the presented information should
be directed to ClinicalTrials.gov.
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