Featured Clinical Trials Supported by the National Cancer Institute
Today, thousands of cancer clinical trials are under way in the United States. Clinical trials answer vital research questions that lead to better screening, prevention, diagnosis, and treatment options for all cancers. This section highlights NCI-supported cancer trials and demonstrates the breadth of clinical cancer research supported by the Institute.
To find other cancer trials open to enrollment:
- Call NCI's Cancer Information Service at 1-800-4-CANCER (1-800-422-6237) for information about trials all across the country. The call is toll-free and completely confidential.
- Use the clinical trials search form to look online for trials listed on NCI's Cancer.gov Web site. The form has a Help link for tips about searching for clinical trials.
- For information about cancer trials taking place on the National Institutes of Health campus in Bethesda, Maryland, call NCI’s Clinical Trials Referral Office at 1-888-NCI-1937 (1-888-624-1937). The call is toll-free and completely confidential.
(Posted: 05/15/2012) - In this trial, patients with unresectable hepatocellular carcinoma who are ineligible for liver transplants or other localized therapies, and who did not benefit from or could not tolerate treatment with sorafenib, will be treated with intravenous TRC105 every 2 weeks.
Surgical and Radiation Therapies for High-Risk Early Lung Cancer
(Posted: 05/01/2012) - Patients with high-risk operable stage I lung cancer will be randomly assigned to undergo either sublobar resection, with or without brachytherapy, or stereotactic body radiation therapy.
Testing Vascular Disruption Combined with Chemotherapy for Advanced Solid Tumors
(Posted: 04/17/2012) - In this phase I/II trial, doctors will assess the safety and tolerability of intravenous crolibulin and cisplatin in patients with advanced solid tumors, establish the maximum tolerated dose for the combination, and randomly assign patients with anaplastic thyroid cancer to receive crolibulin and cisplatin or cisplatin alone.
Virus Therapy for Extensive-Stage Small Cell Lung Cancer
(Posted: 04/03/2012) - In this clinical trial, patients with extensive-stage small cell lung cancer who have received platinum-based chemotherapy will be randomly assigned to receive Seneca Valley virus-001 intravenously or an intravenous placebo.
Combining Systemic Therapies for Patients with Advanced Liver Cancer
(Posted: 03/20/2012) - In this phase III trial, patients with unresectable, locally advanced or metastatic primary liver cancer who have good liver function (Child-Pugh score A) will receive sorafenib and be randomly assigned to also receive either doxorubicin or no additional therapy.