Screening and Testing to Detect Prostate Cancer
Researchers are working on developing effective methods to screen for prostate cancer. However, it has not yet been shown that screening for prostate cancer decreases the chances of dying from prostate cancer.
On this page:
Prostate Cancer Screening Summary
Prostate-Specific Antigen (PSA)
- Prostate-Specific Antigen (PSA) Test
A fact sheet that describes the PSA screening test for prostate cancer and explains the benefits and limitations of the test.
- PSA Screening Leads to Aggressive Treatment, Even in Older Men at Low Risk
Screening for prostate cancer with the prostate-specific antigen (PSA) test has led to overtreatment of many prostate cancers, including aggressive treatments in older men considered to be at low risk for progression of the disease according to a study published in the July 26, 2010 Archives of Internal Medicine.
- Panel Recommends Against PSA Testing in Men 75 or Older
The U.S. Preventive Services Task Force is advising against the routine use of prostate-specific antigen (PSA) testing to screen for prostate cancer in men age 75 and older, according to guidelines published in the August 5, 2008, Annals of Internal Medicine.
- Benefits and Harms of PSA Screening for Prostate Cancer
As more has been learned about the benefits and harms of PSA screening, organizations have begun to recommend against routine screening.
Find Clinical Trials to Screen for Prostate Cancer
Check for prostate cancer screening trials from NCI's list of cancer clinical trials now accepting patients. The list of clinical trials can be refined by location and other features.
Research About Prostate Cancer Screening
- Long-Term Trial Results Show No Mortality Benefit from Annual Prostate Cancer Screening
Thirteen year follow-up data from the Prostate, Lung, Colorectal and Ovarian (PLCO) cancer screening trial show higher incidence but similar mortality among men screened annually with the prostate-specific antigen (PSA) test and digital rectal examination (DRE).
- Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial
A large-scale clinical trial to determine whether certain cancer screening tests reduce deaths from prostate, lung, colorectal, and ovarian cancer. In addition, there are numerous epidemiologic and ancillary studies going on that will answer other crucial questions about these cancers and these screening tests.
Prostate Changes and Conditions
- Understanding Prostate Changes: A Health Guide for Men
This booklet for men describes changes that may occur in the prostate over time.