Links to NCI MaterialsNumerous studies have suggested that aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) may hold promise in helping to prevent cancer. NSAIDs block cyclooxygenase (COX) enzymes, which are produced by the body when there is inflammation and also by some precancerous tissues.
- Nonsteroidal Anti-Inflammatory Drugs and Cancer Prevention
Information from the Surveillance, Epidemiology, and End Results (SEER) Program of the National Cancer Institute.
- Study Shows Aspirin Reduces Colorectal Cancer in Those at High Risk
Findings from the first large clinical trial of its kind indicate that taking high doses of aspirin daily for at least 2 years substantially reduces the risk of colorectal cancer among people at increased risk of the disease.
- Can Aspirin Reduce Cancer Risk and Mortality?
The prospect is too enticing to dismiss: a single pill—a cheap one, too—that, when taken regularly, can reduce the risk not only of heart attack or stroke, but also of developing or dying from some types of cancer.
- Low-Dose Aspirin Fails to Protect Women Against Cancer
Low-dose aspirin taken every other day failed to protect women from developing cancer, according to results from a 10-year, randomized trial called the Women’s Health Study. However, researchers say that more studies are needed to determine whether moderate or high doses of aspirin may yet prove protective.
- Aspirin Use Is Not Associated with Pancreatic Cancer Mortality, Study Reports
Results from a large U.S. cohort of nearly 1 million adults found that aspirin use was not associated with mortality from pancreatic cancer.
- NCI-Funded Clinical Trials Show Aspirin Reduces Recurrence of Polyps
Taking daily aspirin for as little as three years was shown to reduce the development of colorectal polyps by 19 percent to 35 percent in people at high risk for colorectal cancer in two randomized, controlled clinical trials published in the New England Journal of Medicine.