National Cancer Institute

at the National Institutes of Health

Uterine Sarcoma Treatment (PDQ®)

Health Professional Version

Last Modified: 10/18/2012

Stage Information for Uterine Sarcoma

Definitions: FIGO

The Féderation Internationale de Gynécologie et d’Obstétrique (FIGO) and the American Joint Committee on Cancer (AJCC) have designated staging to define carcinoma of the corpus uteri, which applies to uterine sarcoma; the FIGO system is most commonly used.[1,2]

Uterine sarcomas include leiomyosarcomas, endometrial stromal sarcomas, and adenosarcomas.

Table 1. Uterine Sarcoma^a

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Stage
I^b	Tumor confined to the corpus uteri.
IA^b	No or less than half myometrial invasion.
IB^b	Invasion equal to or more than half of the myometrium.
II^b	Tumor invades cervical stroma but does not extend beyond the uterus.^c
III^b	Local and/or regional spread of the tumor.
IIIA^b	Tumor invades the serosa of the corpus uteri and/or adnexae.^d
IIIB^b	Vaginal and/or parametrial involvement.^d
IIIC^b	Metastases to pelvic and/or para-aortic lymph nodes.^d
IIIC1^b	Positive pelvic nodes.
IIIC2^b	Positive para-aortic lymph nodes with or without positive pelvic lymph nodes.
IV^b	Tumor invades bladder and/or bowel mucosa, and/or distant metastases.
IVA^b	Tumor invasion of bladder and/or bowel mucosa.
IVB^b	Distant metastases, including intra-abdominal metastases and/or inguinal lymph nodes.

^aAdapted from FIGO Committee on Gynecologic Oncology.[1]
^bEither G1, G2, or G3 (G = grade).
^cEndocervical glandular involvement only should be considered as stage I and no longer as stage II.
^dPositive cytology has to be reported separately without changing the stage.

References

Pecorelli S: Revised FIGO staging for carcinoma of the vulva, cervix, and endometrium. Int J Gynaecol Obstet 105 (2): 103-4, 2009. [PUBMED Abstract]
Corpus uteri. In: Edge SB, Byrd DR, Compton CC, et al., eds.: AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer, 2010, pp 403-18.