Cellular Classification of Ovarian Germ Cell Tumors

The following histologic subtypes have been described.[1,2]

• Dysgerminoma.
• Other germ cell tumors:
  • Endodermal sinus tumor (rare subtypes are hepatoid and intestinal).[1]
  • Embryonal carcinoma.
  • Polyembryoma.
  • Choriocarcinoma.
  • Teratoma:
    • Immature.
    • Mature:
      • Solid.
      • Cystic:
        • Dermoid cyst (mature cystic teratoma).
        • Dermoid cyst with malignant transformation.
    • Monodermal and highly specialized:
      • Struma ovarii.
      • Carcinoid.
      • Struma ovarii and carcinoid.
      • Others (e.g., malignant neuroectodermal and ependymoma).
  • Mixed forms.

1. Gershenson DM: Update on malignant ovarian germ cell tumors. Cancer 71 (4 Suppl): 1581-90, 1993.  [PUBMED Abstract]
   
   
2. Serov SF, Scully RE, Robin IH: International Histologic Classification of Tumours: No. 9. Histological Typing of Ovarian Tumours. Geneva: World Health Organization, 1973.