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Langerhans Cell Histiocytosis Treatment (PDQ®)

Health Professional Version
Last Modified: 05/22/2013

Changes to the Summary (05/22/2013)

The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.

Childhood LCH

Revised text to state that solvent exposure in parents, family history of cancer, and perinatal infections have a weak association with LCH, but there is no increase in cases after viral epidemics (cited Venkatramani et al. as reference 13). Also revised text to state that an increased frequency of family members with thyroid disease has been reported in white patients.

Presentation of LCH in Children

Added Abbritti et al. as reference 21.

Treatment of Adult LCH

Added Abbritti et al. as reference 4.

This summary is written and maintained by the PDQ Pediatric Treatment Editorial Board, which is editorially independent of NCI. The summary reflects an independent review of the literature and does not represent a policy statement of NCI or NIH. More information about summary policies and the role of the PDQ Editorial Boards in maintaining the PDQ summaries can be found on the About This PDQ Summary and PDQ NCI's Comprehensive Cancer Database pages.