Table 8. Chronic Graft-versus-Host Disease (GVHD) Symptoms in the Mouth and GI Tracta
| Organ or Site | Diagnosticb | Distinctivec | Other Featuresd | Common (Seen with Both Acute and Chronic GVHD) |
| Mouth | Lichen-type features | Xerostomia | | Gingivitis |
| Hyperkeratotic plaques | Mucocele | Mucositis |
| Restriction of mouth opening from sclerosis | Pseudomembranese | Erythema |
| Mucosal atrophy | Pain |
| Ulcerse | |
|
| GI Tract | Esophageal web | | Exocrine pancreatic insufficiency | Anorexia |
| Strictures or stenosis in the upper to mid third of the esophaguse | Nausea |
| Vomiting |
| Diarrhea |
| Weight loss |
| Failure to thrive (infants and children) |
| Total bilirubin, alkaline phosphatase >2 × ULNe |
| ALT or AST >2 × ULNe |
| ALT = alanine aminotransferase; AST = aspartate aminotransferase; GI = gastrointestinal; ULN = upper limit of normal. |
| Refer to Table 7 footers for definitions of a through e. |
