Table 1. National Cancer Institute’s Common Terminology Criteria for Adverse Events: N&Va
| Adverse Event | Grade | Description |
| Nauseab | 1 | Loss of appetite without alteration in eating habits |
| 2 | Oral intake decreased without significant weight loss, dehydration, or malnutrition | |
| 3 | Inadequate oral caloric or fluid intake; tube feeding, TPN, or hospitalization indicated | |
| 4 | Grade not available | |
| 5 | Grade not available | |
| Vomitingc | 1 | 1–2 episodes (separated by 5 min) in 24 h |
| 2 | 3–5 episodes (separated by 5 min) in 24 h | |
| 3 | ≥6 episodes (separated by 5 min) in 24 h; tube feeding, TPN, or hospitalization indicated | |
| 4 | Life-threatening consequences; urgent intervention indicated | |
| 5 | Death |
| N&V = nausea and vomiting (emesis); TPN = total parenteral nutrition. | ||
| aAdapted from National Cancer Institute.[10] | ||
| bDefinition: A disorder characterized by a queasy sensation and/or the urge to vomit. | ||
| cDefinition: A disorder characterized by the reflexive act of ejecting the contents of the stomach through the mouth. |
References
- National Cancer Institute.: Common Terminology Criteria for Adverse Events (CTCAE), Version 4.0. Bethesda, Md: U.S. Department of Health and Human Services, National Institutes of Health, 2010. Available online. Last accessed March 28, 2013.
