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Hypercalcemia (PDQ®)

  • Updated: 01/09/2013

Table 1. Incidence of Hypercalcemia by Tumor Typea

Tumor Type Incidence (%) of Hypercalcemia of Malignancy 
aAdapted from Kaplan.[1]
Breast (with bone metastases)30–40
Multiple myeloma20–40
Squamous cell carcinoma of lung12.5–35
Squamous cell carcinoma of head and neck2.9–25
Renal cell carcinoma3–17
Lymphomas
Hodgkin lymphoma0.6–5.4
Non-Hodgkin lymphoma, high-grade14–33
T-cell lymphoma (human T-cell, lymphotrophic virus type 1)50
Other malignancies: ovary, liver, pancreas, esophagus, cervix7
Unknown primary7

References

  1. Kaplan M: Hypercalcemia of malignancy. In: Yarbro CH, Wujcik D, Gobel BH, eds.: Cancer Nursing: Principles and Practice. 7th ed. Sudbury, Mass: Jones and Bartlett Publishers, 2010, pp 939-63.