Changes to This Summary (03/30/2012)
The PDQ cancer information summaries are reviewed regularly and updated as new information becomes available. This section describes the latest changes made to this summary as of the date above.
Added text about a large cohort study that found an association between daily or weekly nonaspirin nonsteroidal anti-inflammatory drug use and reduced 10-year incidence of proximal and distal, but not rectal, colorectal cancer (cited Ruder et al. as reference 37).
Added text about a large cohort study that found an association between daily or weekly aspirin use and reduced 10-year incidence of distal and rectal, but not proximal, colorectal cancer.

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