Table 1. Relative Risk (RR) Related to Family History of Prostate Cancera
| Risk Group | RR for Prostate Cancer (95% CI) |
| Brother with prostate cancer diagnosed at any age | 3.4 (3.0–3.8) |
| Father with prostate cancer diagnosed at any age | 2.2 (1.9–2.5) |
| One affected FDR diagnosed at any age | 2.6 (2.3–2.8) |
| One affected second-degree relative diagnosed at any age | 1.7 (1.1–2.6) |
| Affected FDRs diagnosed age <65 y | 3.3 (2.6–4.2) |
| Affected FDRs diagnosed age >65 y | 2.4 (1.7–3.6) |
| Two or more affected FDRs diagnosed at any age | 5.1 (3.3–7.8) |
| CI = confidence interval; FDR = first-degree relative. | |
| aAdapted from Zeegers et al.[40] |
References
- Zeegers MP, Jellema A, Ostrer H: Empiric risk of prostate carcinoma for relatives of patients with prostate carcinoma: a meta-analysis. Cancer 97 (8): 1894-903, 2003. [PUBMED Abstract]
