Comparative Study of Chemotherapy for B-Cell Lymphoma
Name of the Trial
Why Is This Trial Important?
Bortezomib, one of a new class of targeted anticancer drugs called proteasome inhibitors, has shown effectiveness against relapsed (worsening after a period of improvement) or refractory (treatment-resistant) blood-cell cancers in other clinical studies. This trial will compare bortezomib alone against bortezomib added to a chemotherapy combination known as EPOCH (etoposide, prednisone, vincristine, cyclophosphamide, and doxorubicin) to see which is more effective in fighting relapsed or refractory large B-cell lymphoma.
"Because bortezomib targets a pathway important in certain types of diffuse large B-cell lymphoma, we hope that it will make these tumors more sensitive to chemotherapy and, perhaps, even cause tumors to shrink on their own" said Dr. Wilson.
"EPOCH already has been shown to be a very good regimen for people with this disease," Dr. Wilson added. "With this study, the first to combine bortezomib and EPOCH, we hope to see the agents work in synergy to produce even better results."
Who Can Join This Trial?
Where Is This Trial Taking Place?
Who To Contact
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